Results 111 to 120 of about 29,393,528 (376)

Embedding consumer and community involvement in antenatal healthcare research: A methodological approach and perspectives of culturally and linguistically diverse women in Australia

Research Involvement and Engagement
Background Consumer and Community Involvement (CCI) in healthcare research ensures that the needs of target populations are met through active collaboration between consumers, communities, and researchers. For culturally and linguistically diverse (CALD)
Bonnie R. Brammall, Rebecca L. Madill, Rhonda M. Garad, Bao N. Nguyen, Nitya Nagesh, Cheryce L. Harrison   +5 more
doaj   +1 more source

How is implementation research applied to advance health in low-income and middle-income countries?

BMJ Global Health, 2019
This paper examines the characteristics of implementation research (IR) efforts in low-income and middle-income countries (LMICs) by describing how key IR principles and concepts have been used in published health research in LMICs between 1998 and 2016,
O. Alonge, D. Rodriguez, N. Brandes, E. Geng, L. Reveiz, D. Peters   +5 more
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Implementation of Community Policing Strategy: Impact of Community Factors in Nairobi Country [PDF]

, 2019
Crime is a community problem and not just a police problem. The adoption and implementation of Community Policing (CP) in the 1980s, was perceived as departure from the professional ‘police-as- expert’ model of public safety that had been dominant for a ...
Kabage, Robert Gichangi
core  

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Determinants of implementation of continuous glucose monitoring for patients with Insulin-Treated type 2 diabetes: a national survey of primary care providers

BMC Primary Care
Objectives To identify determinants of continuous glucose monitoring (CGM) implementation from primary care providers’ (PCPs’) perspectives and examine the associations of these determinants with both PCP intent to discuss CGM with eligible patients and ...
Varsha G. Vimalananda, Ben Kragen, Alison J. Leibowitz, Shirley Qian, Jolie Wormwood, Amy M. Linsky, Patricia Underwood, Paul R. Conlin, Bo Kim   +8 more
doaj   +1 more source

Measures of outer setting constructs for implementation research: A systematic review and analysis of psychometric quality

Implementation Research and Practice, 2020
Background: Despite their influence, outer setting barriers (e.g., policies, financing) are an infrequent focus of implementation research. The objective of this systematic review was to identify and assess the psychometric properties of measures of ...
S. McHugh, Caitlin N. Dorsey, Kayne D. Mettert, Jonathan Purtle, E. Bruns, C. Lewis   +5 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Understanding Perceptions of Hepatitis C and Its Management Among People with Experience of Incarceration in Quebec, Canada: A Qualitative Study Guided by the Common Sense Self-Regulation Model

Viruses
Hepatitis C virus (HCV) disproportionately affects certain sub-populations, including people with experience of incarceration (PWEI). Little is known about how perceptions of HCV and treatment have changed despite simplifications in testing and treatment
Andrea Mambro, Sameh Mortazhejri, David Ortiz-Paredes, Andrea Patey, Guillaume Fontaine, Camille Dussault, Joseph Cox, Jeremy M. Grimshaw, Justin Presseau, Nadine Kronfli   +9 more
doaj   +1 more source