Results 121 to 130 of about 28,489,203 (383)

Toward optimal implementation of cancer prevention and control programs in public health: A study protocol on mis-implementation [PDF]

, 2018
Background Much of the cancer burden in the USA is preventable, through application of existing knowledge. State-level funders and public health practitioners are in ideal positions to affect programs and policies related to cancer control.
A McGowan, A Strauss, A Strauss, AA Vincus, AH Mokdad, AJR Carter, AL Harris, American Cancer Society, B Rabin, BA Rabin, BA Rabin, Benjamin Heuberger, BH Forsyth, BY Lee, C Maylahn, CE Basch, D Ciliska, D Dillman, D Gnjidic, D Luke, D Pourshaban, DA Luke, DA Marshall, DE Gibbons, Doug A. Luke, E Bonabeau, E Bruch, E Hennessy, E Larsen, EA Dodson, EM Rogers, G Dunn, G Fioretti, GA Aarons, GA Colditz, GM Higginbottom, Institute of Medicine, J Epstein, J Harrison, J-O Kim, JA Jacobs, JA Jacobs, JB Jobe, JB Jobe, JG Burke, JH Miller, JR Landis, KA Bollen, L Elliott, L Kohn, L Rychetnik, L Yarber, LA Curry, LW Green, M Dobbins, M Dreisinger, M Huhman, M Maclure, MA O’Neall, MA Pett, MA Sanchez, MA Sastry, Margaret Padek, Matt Kasman, Melissa Franco, MQ Patton, ND Kohatsu, P Allen, P Ballew, P Brewer Gad, P Drehobl, P Ellis, P Gagne, P Glasziou, P Noriega, PA Briss, PA Hannon, Paul C. Erwin, PC Erwin, Peg Allen, PS Hovmand, PW Rochester, RA Hammond, RA Nianogo, RB Gunderman, RC Brownson, RC Brownson, RC Brownson, RC Brownson, RC Brownson, RC Brownson, RC Brownson, Ross A. Hammond, Ross C. Brownson, RR Jacob, RR Massatti, S Feirman, S Kreitner, S Kumar, Sarah Moreland-Russell, SL West, ST Brown, Stephanie Mazzucca, T Byers, TK Boehmer, V Prasad, WC Willett, WS Gibbert   +107 more
core   +2 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Implementation Research Methodologies for Achieving Scientific Equity and Health Equity.

Ethnicity & Disease, 2019
Implementation science has great potential to improve the health of communities and individuals who are not achieving health equity. However, implementation science can exacerbate health disparities if its use is biased toward entities that already have ...
M. McNulty, Justin D. Smith, J. Villamar, Inger E. Burnett-Zeigler, Wouter Vermeer, N. Benbow, Carlos G Gallo, U. Wilensky, A. Hjorth, B. Mustanski, J. Schneider, C. Brown   +11 more
semanticscholar   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Surfacing ERP exploitation risks through a risk ontology [PDF]

, 2009
Purpose – The purpose of this paper is to develop a risk identification checklist for facilitating user companies to surface, organise and manage potential risks associated with the post-adoption of Enterprise Resource Planning (ERP) systems ...
Nunes, J.M.B., Peng, Guo Chao
core   +2 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Developing measures to assess constructs from the Inner Setting domain of the Consolidated Framework for Implementation Research

Implementation Science, 2018
BackgroundScientists and practitioners alike need reliable, valid measures of contextual factors that influence implementation. Yet, few existing measures demonstrate reliability or validity.
Maria E. Fernandez, Timothy J. Walker, B. Weiner, W. Calo, Shuting Liang, B. Risendal, D. Friedman, S. Tu, Rebecca S. Williams, S. Jacobs, Alison K Herrmann, M. Kegler   +11 more
semanticscholar   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

A method to reduce imbalance for site-level randomized stepped wedge implementation trial designs

Implementation Science, 2019
Background Controlled implementation trials often randomize the intervention at the site level, enrolling relatively few sites (e.g., 6–20) compared to trials that randomize by subject.
Robert A. Lew, Christopher J. Miller, Bo Kim, Hongsheng Wu, Kelly Stolzmann, Mark S. Bauer   +5 more
doaj   +1 more source

The Development of Inclusive Education Management Model: Practical Guidelines for Learning in Inclusive School [PDF]

, 2020
This research aimed to explore the current conditions, problems, and needs in the implementation of inclusive education, to examine the best model of the implementation of inclusive education and to investigate the effectiveness of the inclusive ...
Mudjito, M. (Mudjito), Murtadlo, M. (Murtadlo), Robiyansah, I. E. (Iva)   +2 more
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