Results 91 to 100 of about 3,288,592 (272)
Implementation Mapping: Using Intervention Mapping to Develop Implementation Strategies
Frontiers in Public Health, 2019 Background: The ultimate impact of a health innovation depends not only on its effectiveness but also on its reach in the population and the extent to which it is implemented with high levels of completeness and fidelity.
Maria E. Fernandez +10 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
, 2011 We study single-good auctions in a setting where each player knows his own valuation only within a constant multiplicative factor \delta{} in (0,1), and the mechanism designer knows \delta.
Chiesa, Alessandro +2 more
core +1 more source
Journal of Clinical and Translational ScienceIntroduction: Community advisory boards (CABs) are a promising approach for strengthening patient and partner voices in community health center (CHC) evidence-based decision-making.
Rebekka M. Lee +6 more
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Understanding the implementation of e-business strategies: Evidence from Luxembourg [PDF]
Our empirical study aims at identifying the drivers of the implementation of an e-business strategy by firms located in Luxembourg. The setting up of such a strategy is apprehended through the website and the type of strategy through the functionalities ...
Martin, Ludivine
core +1 more source
What Works at Scale? Distilling the Critical Success Factors for Scaling Up Rural Sanitation [PDF]
, 2014 This paper is based on the Knowledge Sharing Forum of the same name. It examines the conditions for success in sanitation programs and strategies that lead to robust implementation in various ...
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source