Results 161 to 170 of about 78,098 (296)

PixelDeck: A local-first media library manager for biomedical imaging. [PDF]

SoftwareX
Kidder BL.
europepmc   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

TESTING PROTECTION FOR SALE IN THE FOOD INDUSTRIES [PDF]

This paper tests the Grossman-Helpman Protection for Sale model using panel data from U.S. food processing industries with endogenous protection, import penetration, and political campaign.
Hathie, Ibrahima, Lopez, Rigoberto A.
core  

Setting of an import tolerance for fenazaquin in teas. [PDF]

EFSA J
European Food Safety Authority (EFSA), Bellisai G, Bernasconi G, Castellan I, Del Aguila M, Ferreira L, Leuschner R, Mioč A, Szot M, Tiramani M, Verani A.   +10 more
europepmc   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Chloroplastic protein prenylation: an internal or external affair? Reconciling biochemical data through a new hypothesis. [PDF]

Front Plant Sci
Luo M, Chi W.
europepmc   +1 more source

Assessment of genetically modified maize MON 87411 for food and feed uses, import and processing, under Regulation (EC) No 1829/2003 (application EFSA-GMO-NL-2015-124). [PDF]

EFSA J, 2018
EFSA Panel on Genetically Modified Organisms (GMO), Naegeli H, Birch AN, Casacuberta J, De Schrijver A, Gralak MA, Guerche P, Jones H, Manachini B, Messéan A, Nielsen EE, Nogué F, Robaglia C, Rostoks N, Sweet J, Tebbe C, Visioli F, Wal JM, Ardizzone M, De Sanctis G, Fernandez Dumont A, Gennaro A, Gómez Ruiz JA, Lanzoni A, Neri FM, Papadopoulou N, Paraskevopoulos K, Ramon M.   +27 more
europepmc   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Mitochondrial protein import [PDF]

, 1990
Pfanner, Nikolaus, Neupert, Walter
core   +1 more source

Proteolytic control of mitochondrial protein translocases. [PDF]

Protein Sci
Kroczek L, Langer T.
europepmc   +1 more source