Results 61 to 70 of about 490,177 (259)

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

Influence of temperature and packaging on physiological and chemical profiles of imported litchi fruit [PDF]

open access: yes, 2011
The aim of this study was to detail the physiological and biochemical changes in non-adulterated and commercially-treated litchi fruit stored in different packaging films under different storage temperatures. Litchi fruit cv.
Somboonkaew, Nettra   +3 more
core   +1 more source

Analysis of systems behaviour in the absorption of imported technology

open access: yes, 1983
Meeting: Absorption and Diffusion of Imported Technology, 26-30 Jan. 1981, Singapore, SGMeeting: Research and Policy Workshop on Technology Problems for the Caribbean, 13 Nov.-10 Dec.
Suck Chul Yoon
core   +1 more source

Description of the Serological Response After Treatment of Chronic Imported Schistosomiasis

open access: yesTropical Medicine and Infectious Disease
Background: Chronic schistosomiasis can lead to significant morbidity. Serology is highly sensitive; however, its role in assessing treatment response is controversial.
Marta González-Sanz   +9 more
doaj   +1 more source

Ethical Foreground and Background in Adult Educator Work

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Fire Ant Trails

open access: yes, 1998
Monthly newsletter from the Texas Imported Fire Ant Research & Management Plan providing updates about news, events, and other information of interest to the Department of ...
Texas Imported Fire Ant Research & Management Plan   +1 more
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Imported Inputs and Productivity [PDF]

open access: yes
We estimate a model of importers in Hungarian micro data and conduct counterfactual policy analysis to investigate the effect of imports on productivity.
Miklós Koren   +2 more
core  

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs   +7 more
wiley   +1 more source

Derived Demand for Fresh Cheese Products Imported into Japan [PDF]

open access: yes
The objective of this article is to estimate the derived demand for imported fresh cheese products into Japan when fresh cheese import data are disaggregated by source country of production.
Stearns, James A.   +4 more
core  

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