Results 71 to 80 of about 419,250 (318)

Prices and availability of locally produced and imported medicines in Ethiopia and Tanzania

open access: yesJournal of Pharmaceutical Policy and Practice, 2017
Background To assess the effect of policies supporting local medicine production to improve access to medicines. Methods We adapted the WHO/HAI instruments measuring medicines availability and prices to differentiate local from imported products, then ...
M. Ewen   +8 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Description of the Serological Response After Treatment of Chronic Imported Schistosomiasis

open access: yesTropical Medicine and Infectious Disease
Background: Chronic schistosomiasis can lead to significant morbidity. Serology is highly sensitive; however, its role in assessing treatment response is controversial.
Marta González-Sanz   +9 more
doaj   +1 more source

p53 stabilization: the importance of nuclear import [PDF]

open access: yesCell Death & Differentiation, 2010
In response to cellular stress, the p53 tumor suppressor protein is stabilized as a result of inactivation of ubiquitin-mediated degradation. The p53 protein rapidly accumulates in the nucleus, where it functions as a transcription factor. Although the regulation of p53 stability has been studied extensively, the subcellular compartment in which p53 ...
openaire   +2 more sources

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Imported Inputs and Productivity [PDF]

open access: yes
We estimate a model of importers in Hungarian micro data and conduct counterfactual policy analysis to investigate the effect of imports on productivity.
Miklós Koren   +2 more
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Imported intermediary inputs, R&D and Firm's Productivity: Evidence from Indian Manufacturing [PDF]

open access: yes
This paper examines dynamic as well as static effects of imported intermediary inputs and inhouse R&D on productivity growth using firm-level panel data for Indian technology-intensive manufacturing industries for the period 2000-2009.
Sharma, Chandan
core  

Clinical and epidemiological characteristics of imported intestinal infections in children

open access: yesДетские инфекции (Москва)
Since the beginning of the 21st century, the number of international trips has been increasing in the world. Outbound and domestic tourism is expanding in Russia.
E. Yu. Pylaeva   +13 more
doaj   +1 more source

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