Results 111 to 120 of about 1,300,694 (272)

Nickel Intercalation in Epitaxial Graphene on SiC(0001): A Novel Platform for Engineering Two‐Dimensional Heterostructures

Advanced Science, EarlyView.
Ni‐intercalated graphene on SiC is achieved through a scalable colloidal nanoparticle deposition route. 2D heterostructures show preserved graphene band structure, stable under ambient conditions, and robust interfacial magnetism. Intercalated 2D Ni represents a promising candidate for next‐generation spintronic devices and is a scalable pathway to ...
Ylea Vlamidis, Stiven Forti, Antonio Rossi, Arrigo Calzolari, Carmela Marinelli, Camilla Coletti, Stefan Heun, Stefano Veronesi   +7 more
wiley   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Possibilities and Limitations of Prenatal Diagnosis of Rare Imprinting Syndromes: Prader–Willi Syndrome

Children
Background: Prader–Willi syndrome (PWS) is a multisystemic complex imprinting disorder. Prenatal diagnosis of PWS is still a challenge with non-specific ultrasound markers and limitations for diagnosis with non-invasive screening methods.
Simona Anzhel, Nikolinka Yordanova, Emil Kovachev, Darina Krumova, Elis Ismail   +4 more
doaj   +1 more source

Imprinting disorders and in vitro fertilization

, 2023
ZusammenfassungSeit der ersten extrakorporalen Befruchtung 1978 hat dieses Verfahren die Geburt von über 8 Millionen Kindern ermöglicht (Bart, 2019).
Saxer Gogos, Helene
core   +1 more source

Microfluidic Gratings for X‐Ray Phase Contrast Imaging

Advanced Science, EarlyView.
This work establishes a new protocol for the fabrication of X‐ray gratings that exploits the advantages of microfluidics and enables a more inexpensive, faster, and scalable production process. These X‐ray devices are fundamental for implementing X‐ray phase contrast imaging (XPCI) in laboratory and clinical settings, yet their costly and complex ...
Alessandro Rossi, Antonio Ferraro, Francesco Coccimiglio, Tiziana Ritacco, Alberto Astolfo, Michele Giocondo, Vincenzo Formoso, Raffaele Giuseppe Agostino, Francesco Iacoviello, Ioannis Papakonstantinou, Alessandro Olivo   +10 more
wiley   +1 more source

A case of an Angelman-syndrome caused by an intragenic duplication of UBE3A uncovered by adaptive nanopore sequencing

Clinical Epigenetics
Adaptive nanopore sequencing as a diagnostic method for imprinting disorders and episignature analysis revealed an intragenic duplication of Exon 6 and 7 in UBE3A (NM_000462.5) in a patient with relatively mild Angelman-like syndrome.
Laura Holthöfer, Stefan Diederich, Verena Haug, Lioba Lehmann, Charlotte Hewel, Norbert W. Paul, Susann Schweiger, Susanne Gerber, Matthias Linke   +8 more
doaj   +1 more source

DNA methylation analysis

Swiss Medical Weekly, 2013
DNA methylation, the addition of a methyl group to cytosines and adenosines, regulates gene expression on a level that is usually referred to as epigenetic, that is, stably maintained during cell divisions.
Thomas von Känel, Andreas R Huber
doaj   +1 more source

Promising therapeutic aspects in human genetic imprinting disorders. [PDF]

Clin Epigenetics, 2022
Chao Y, Qin Y, Zou X, Wang X, Hu C, Xia F, Zou C.   +6 more
europepmc   +1 more source

Genomic imprinting: concept and clinical consequences

, 1999
One of the major discoveries in modern genetics is the phenomenon of genomic, or parental, imprinting. The parent-of-origin effects seen after transmission of an imprinted gene from parents to their children do not follow the genetic rules postulated by ...
Mannens, M., Alders, M.
core   +1 more source

Identification of imprinted genes subject to parent-of-origin specific expression in Arabidopsis thaliana seeds [PDF]

, 2011
BACKGROUND: Epigenetic regulation of gene dosage by genomic imprinting of some autosomal genes facilitates normal reproductive development in both mammals and flowering plants.
Laouielle-Duprat, S., Prins, Pjotr, Prins, P, Donoghue, M T A, Wennblom, T J, Wennblom, T.J., Duszynska, Dorota, Comte, Aurélie, Lao Nga, Fort, A., Spillane Charles, Marc W Schmid, Smant, G., Köhler, C, Duszynska, D., Lao, N.T., Prins, J.C.P., Nga Thi Lao, Lao, N., Prins Pjotr, Sylvia Laouielle-Duprat, Claudia Köhler, Comte, A, Geert Smant, Köhler, Claudia, Pjotr Prins, Grossniklaus, Ueli, Duszynska, D, Lao, N T, Philip Wolff, McKeown Peter C, Wolff, Philip, Spillane, C., McKeown, P., Ueli Grossniklaus, de Wolff, P., Schmid Marc W, Spillane, C, Wolff Philip, Comte, A., Grossniklaus, U, Wennblom Trevor J, McKeown, Peter C., Wolff, P., Wennblom, T., Köhler Claudia, Schmid, M W, Nga Lao, Donoghue, Mark T.A., Trevor J Wennblom, Schmid, M., Donoghue, M., Spillane, Charles, Smant, G, Wennblom, Trevor J., McKeown, P C, Smant Geert, Wolff, P., de, Duszynska Dorota, Wolff, P, Lao, Nga Thi, Fort, A, Peter C McKeown, Laouielle-Duprat Sylvia, Mark TA Donoghue, Donoghue, M.T., Comte Aurélie, Schmid, Marc W., Donoghue Mark TA, Smant, Geert, Antoine Fort, Grossniklaus, U., Dorota Duszynska, Prins, P., Köhler, C., Laouielle-Duprat, S, Schmid, M.W., Grossniklaus Ueli, Fort Antoine, Fort, Antoine, Aurélie Comte, Laouielle-Duprat, Sylvia, Mckeown, P.C., Charles Spillane   +83 more
core   +1 more source