Results 111 to 120 of about 253 (133)

Improvac does not modify the expression and activities of the major drug metabolizing enzymes cytochrome P450 3A and 2C in pigs

Vaccine, 2012
In the present study, we investigated hepatic mRNA expression and activities of CYP3A and 2C in entire, surgically castrated and pigs vaccinated with Improvac. Additionally, we examined the mRNA expression of the two nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR), known to regulate CYP3A and 2C mRNA expression ...
Martin Krøyer Rasmussen, Galia Zamaratskaia, Bo Ekstrand   +2 more
exaly   +3 more sources

Long-term effect of vaccination against gonadotropin-releasing hormone, using Improvac™, on hormonal profile and behaviour of male pigs

Animal Reproduction Science, 2008
The objective of this study was to evaluate the long-term effect of a gonadotropin-releasing hormone (GnRH) vaccine, Improvac (Pfizer Ltd.), on the levels of GnRH antibodies, testosterone, estrone sulphate (E1S) and androstenone, as well as skatole and indole in male pigs.
Lotta Rydhmer, Galia Zamaratskaia, Kerstin Lundström   +2 more
exaly   +3 more sources

Oestrus suppression in a dairy herd by means of anti-GnRH vaccination Improvac®: A prospective field study

Schweiz Arch Tierheilkd, 2020
The aim of this study was to evaluate the duration of estrus suppression after a double administration of the anti-GnRH vaccine Improvac® (Zoetis Schweiz GmbH, 2800 Delémont) in cows. Furthermore, it should be investigated, if a third administration could prolong the effect of the cycle suppression. A total of 21 cows (more than four weeks post partum)
Schmid R, Studer E, Hirsbrunner G
openaire   +3 more sources

Effect of vaccination against gonadotrophin-releasing hormone, using Improvac®, on growth performance, body composition, behaviour and acute phase proteins [PDF]

Livestock Science, 2010
The objective of this study was to evaluate the effect of vaccination against GnRH on performance traits, pig behaviour and acute phase proteins. A total of 120 pigs (36 non-castrated males, NCM; 36 males to be vaccinated, IM; 24 castratedmales, CM; and 24 females, FE)were controlled in groups of 12 in pens with feeding stations allowing the recording ...
Emma Fàbrega-Romans, Antonio Velarde, J Tibau   +2 more
exaly   +3 more sources

Two complementary methods to control gonadotropin‐releasing hormone vaccination (Improvac®) misuse in horseracing: Enzyme‐linked immunosorbent assay test in plasma and steroidomics in urine [PDF]

Drug Testing and Analysis, 2017
Since the availability on the European market of the vaccine Improvac® dedicated to male pig immunological castration, the risk of misuse of this product in horses is now considered as a threat for the horseracing industry. Immunological castration is not allowed by the racing codes (immune system, Article 6).
Benoit Loup, Patrice Garcia, Ludovic Bailly-Chouriberry   +2 more
exaly   +3 more sources

Short- and long-term effects of immunization against gonadotropin-releasing hormone, using Improvac™, on sexual maturity, reproductive organs and sperm morphology in male pigs

Theriogenology, 2009
The objective of this study was to determine the short and long term effects of a gonadotropin-releasing hormone (GnRH) vaccine (Improvac Pfizer Ltd.), on sexual maturity, development of the reproductive organs, and the morphology of caudal epididymal spermatozoa in non-castrated male pigs.
Heriberto Rodríguez-Martínez, K Lundström, M Wallgren   +2 more
exaly   +3 more sources

Effect of a Gonadotropin‐releasing Hormone Vaccine (Improvac^TM) on Steroid Hormones, Boar Taint Compounds and Performance in Entire Male Pigs

Reproduction in Domestic Animals, 2007
ContentsThe objective of this study, comprising two trials, was to evaluate the effect of a gonadotropin‐releasing hormone (GnRH‐vaccine ImprovacTM; Pfizer Ltd) in a sample of the Swedish pig population. The pigs (n = 120) were assigned to three groups: control (entire male pigs), surgical castration and immunization against GnRH.
G, Zamaratskaia, H K, Andersson, G, Chen, K, Andersson, A, Madej, K, Lundström   +5 more
openaire   +2 more sources

Improvac® Immunized Boars Compared to Surgical Castrates: Control of Boar Taint and Growth Performance

2006
E.T.F. Silveira, E. Poleze, O. Umehara, A.P. Tonietti, M.L.T. Buzelli, M.M.H Haguiwara, L. Miyagusku, D. Hennessy   +7 more
exaly   +2 more sources

Growth performance and carcass characteristics of Improvac-treated male pigs compared with barrows.

Berliner und Munchener tierarztliche Wochenschrift, 2014
The present study assessed the effects of using Improvac (Pfizer Animal Health, Germany) on growth performance and meat characteristics in cross-bred male pigs. In addition average daily weight gain of immunised and surgically castrated males was estimated in order to demonstrate differences in growing patterns in these two treatment groups.
Anna, Albrecht, Elisabeth, Grosse Beilage, Martina, Henning, Torsten, Bekendorf, Joachim, Krieter   +4 more
openaire   +1 more source

A GnRF vaccine (Improvac®) and porcine somatotropin (Reporcin®) have synergistic effects upon growth performance in both boars and gilts

Australian Journal of Agricultural Research, 2003
The use of a vaccine (Improvac) directed against gonadotrophin-releasing factor (GnRF), to prevent boar taint in male pigs, is also associated with an increase in feed consumption, growth, and higher deposition of subcutaneous fat. Daily administration of porcine somatotropin (pST) consistently increases average daily gain, and feed conversion ...
I. McCauley, M. Watt, D. Suster, D. J. Kerton, W. T. Oliver, R. J. Harrell, F. R. Dunshea   +6 more
openaire   +1 more source