Results 61 to 70 of about 49,095 (250)

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang   +19 more
wiley   +1 more source

Research on cloud computing resource allocation strategy based on improved ant colony algorithm

open access: yesDianzi Jishu Yingyong, 2022
In actual projects, it is found that if the ant colony algorithm is directly applied to cloud computing resource allocation, there will often be load imbalances, resulting in low resource utilization. And at the same time, the task completion time is too
Liu Dengming   +3 more
doaj   +1 more source

Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance

open access: yesAdvanced Science, EarlyView.
Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes   +4 more
wiley   +1 more source

Optimization of Sightseeing Paths in Tourism Park Based on Improved Ant Colony Algorithm

open access: yesKongzhi Yu Xinxi Jishu
The intelligent navigation system of tourism parks typically functions to recommend diverse sightseeing paths for tourists of different age groups, comprehensively considering factors such as path distances and the geographical location of all the scenic
LIANG Jianheng
doaj   +1 more source

Improved Ant Algorithms for Software Testing Cases Generation

open access: yesThe Scientific World Journal, 2014
Existing ant colony optimization (ACO) for software testing cases generation is a very popular domain in software testing engineering. However, the traditional ACO has flaws, as early search pheromone is relatively scarce, search efficiency is low ...
Shunkun Yang, Tianlong Man, Jiaqi Xu
doaj   +1 more source

Research on green single machine scheduling based on improved ant colony algorithm

open access: yesMeasurement and control (London. 1968), 2021
This paper studies the green single-machine scheduling problem that considers the delay cost and the energy consumption of manufacturing equipment and builds its integrated optimization model.
Dongping Qiao   +4 more
semanticscholar   +1 more source

Evolution of Physical Intelligence Across Scales

open access: yesAdvanced Intelligent Discovery, EarlyView.
By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu   +7 more
wiley   +1 more source

Modeling the Rise of Temperature of Fitting by Combining Fuzzy System and Ant Colony Algorithm

open access: yes工程科学与技术, 2016
:In order to get an accurate and reliable model of the rise of temperature of connection fitting in value hall of UHVDC,a method of fuzzy system combined ant colony algorithm was used.After analyzing the characteristics of basic ant colony algorithm and ...
王刚   +5 more
doaj  

Retinal Vessel Segmentation: A Comprehensive Review From Classical Methods to Deep Learning Advances (1982–2025)

open access: yesAdvanced Intelligent Systems, EarlyView.
Four decades of retinal vessel segmentation research (1982–2025) are synthesized, spanning classical image processing, machine learning, and deep learning paradigms. A meta‐analysis of 428 studies establishes a unified taxonomy and highlights performance trends, generalization capabilities, and clinical relevance.
Avinash Bansal   +6 more
wiley   +1 more source

AI‐Driven Mapping of Seizure Spread Patterns

open access: yesAnnals of Neurology, EarlyView.
Objective The focus of epilepsy research has largely been on seizure onset; however, physicians typically examine the patterns of seizure spread past seizure onset as well. This study aims to align automated seizure analysis with clinical practice, leverage deep learning to standardize seizure annotations that varies among physicians, and understand ...
Andrew Y. Revell   +13 more
wiley   +1 more source

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