Results 51 to 60 of about 36,659 (292)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A Search Method of NN Reducer’s Transmission Ratio

Jixie chuandong, 2022
The transmission ratio of NN reducer is discrete and nonlinear, and the gear matching method determines the volume and stability of a reducer. In previous studies， most scholars tried to find out the key parameters affecting the change of transmission ...
Yifei Lin, Honghua Zhao, Hongkai Wang, Yan Hu, shouyin Lu, Hui Zhang   +5 more
doaj  

Parameter identification of chaotic systems using improved differential evolution algorithm

, 2013
[[abstract]]In this paper, an improved differential evolution algorithm, named the Taguchi-sliding-based differential evolution algorithm (TSBDEA), is proposed to solve the problem of parameter identification for Chen, L? and Rossler chaotic systems. The
Ho, Wen-Hsien;Chou, Jyh-Horng;Guo, Ching-Yi
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Improved Differential Evolution Algorithm to Solve the Advertising Method Selection Problem

Journal of Open Innovation: Technology, Market and Complexity, 2019
This article proposes a methodology to resolve the advertising method selection problem (AdSP). The use of different advertising methods for the same product can generate different responses in terms of the product’s sales volume. Companies selling
Malichan Thongkham, Tassin Srivarapongse
doaj   +1 more source

Memory-Based Differential Evolution Algorithms with Self-Adaptive Parameters for Optimization Problems

Mathematics
In this study, twelve modified differential evolution algorithms with memory properties and adaptive parameters were proposed to address optimization problems.
Shang-Kuan Chen, Gen-Han Wu, Yu-Hsuan Wu
doaj   +1 more source

Camera calibration based on improved differential evolution particle swarm

Measurement + Control, 2023
Aiming at the problem of camera calibration with multiple parameters, this paper proposes the fusion optimization algorithm of improved differential evolution and particle swarm in the calibration of the camera. Adaptive judgment factors is Introduced to
Wei Fu, Lushen Wu
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

An improved adaptive differential evolution algorithm for single unmanned aerial vehicle multitasking

Defence Technology, 2021
Single unmanned aerial vehicle (UAV) multitasking plays an important role in multiple UAVs cooperative control, which is as well as the most complicated and hardest part.
Jian-li Su, Hua Wang
doaj   +1 more source