Results 71 to 80 of about 8,912,801 (239)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

微分进化多目标优化算法研究

open access: yesJixie chuandong, 2013
Some works are done about the multi-objective differential evolution algorithm and the problems of algorithm in mechanical engineering are revealed.Based on the works,the multi-objective differential evolution algorithm is improved and the constrained ...
钱学毅, 迟建华, 吴双
doaj  

Improvement of Levenberg-Marquardt algorithm during history fitting for reservoir simulation

open access: yesPetroleum Exploration and Development, 2016
In order to estimate reservoir parameters more effectively by history fitting, DE (Differential Evolution) was proposed to estimate the optimum damping factor so that the standard Levenberg-Marquardt algorithm was improved, and the improved algorithm was
Xian ZHANG, A A AWOTUNDE
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

The Performance of German Firms in the Business-Related Service Sectors Revisited: Differential Evolution Markov Chain Estimation of the Multinomial Probit Model [PDF]

open access: yes, 2011
Differential evolution, GHK, MCMC, MNP, Service sector, C13, C15, C25, L25,
W. Erno Kuiper   +5 more
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

open access: yesFEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer   +7 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Optimal Reactive Power Dispatch using Improved Differential Evolution Algorithm

open access: yesMajlesi Journal of Electrical Engineering
Reactive power dispatch plays a key role in secure and economic operation of power systems. Optimal reactive power dispatch (ORPD) is a non-linear optimization problem which includes both continues and discrete variables.
Hamid Falaghi, Arsalan Najafi
doaj  

Optimization pitch angle controller of rocket system using improved differential evolution algorithm

open access: yesIJAIN (International Journal of Advances in Intelligent Informatics), 2017
Pitch angle of rocket system is the important parts of the rocket. This part corresponds to the movement of the rocket system. Rocket system is fell into multi-input and multi-output (MIMO) system.
Dwi Lastomo   +2 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

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