Results 41 to 50 of about 423,521 (309)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Numerical analysis of the influence of design parameters on the efficiency of an OWC axial impulse turbine for wave energy conversion [PDF]

, 2019
Oscillating water column (OWC) axial impulse turbines permit the conversion of wave energy into electrical power. Unlike other hydropower units with a mature and well established technology, such turbines have been recently developed, there are still few
Luo, Yongyao, Presas Batlló, Alexandre, Wang, Zhengwei   +2 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Paramagnetic magnetization signals and curious metastable behaviour in field-cooled magnetization of a single crystal of superconductor 2H-NbSe2 [PDF]

, 2015
We present here some newer characteristics pertaining to paramagnetic Meissner effect like response in a single crystal of the low Tc superconducting compound 2H-NbSe2 via a detailed study of effects of perturbation on the field-cooled magnetization ...
Balakrishnan, G., Grover, A. K., Kumar, Santosh, Paul, D. McK, Tomy, C. V.   +4 more
core   +2 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Current Sensor with Optimized Linearity for Lightning Impulse Current Measurement

Sensors
Impulse current measurement technology is widely used in various applications, including lightning protection monitoring in power systems, welding current measurement in aircraft and shipbuilding industries, as well as high-current measurement in pulsed ...
Wenting Li, Yinglong Diao, Feng Zhou, Zhaozhi Long, Shijun Xie, Jiawei Fan, Kangmin Hu, Zhehao Wang   +7 more
doaj   +1 more source

Rolling Bearing Incipient Fault Detection Based on a Multi-Resolution Singular Value Decomposition

Applied Sciences, 2019
The periodic impulse characteristics caused by rolling bearing damage are weak in the incipient failure stage. Thus, these characteristics are always drowned out by background noise and other harmonic interference.
Jiesi Luo, Shaohui Zhang
doaj   +1 more source

Delay Estimator and Improved Proportionate Multi-Delay Adaptive Filtering Algorithm [PDF]

, 2012
This paper pertains to speech and acoustic signal processing, and particularly to a determination of echo path delay and operation of echo cancellers. To cancel long echoes, the number of weights in a conventional adaptive filter must be large.
Sakhnov, K., Simak, B., Verteletskaya, E.   +2 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Numerical Investigation on Hydrodynamic Characteristics of Landslide-Induced Impulse Waves in Narrow River-Valley Reservoirs

IEEE Access, 2020
Landslide-induced impulse waves in a river-valley reservoir region have become a serious threat to life and property intactness. Compared with previous studies focusing on landslides in open-water regions, this article systematically carried out ...
Bin Deng, He Tao, Changbo Jiang, Ke Qu
doaj   +1 more source