Results 51 to 60 of about 1,771,267 (214)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Modelling of Green function in a rectangular room based upon the geometrical-filtration model

Archives of Acoustics, 2014
Significant problem in room acoustic is evaluating an acoustic quality of projected and modernized rooms. Estimation of room impulse response giving posibility to evaluate the subjective and objective room acoustic properties and hence to run the room ...
R. Marczuk, L. Majkut
doaj  

Basis Functions for a Transient Analysis of Linear Commensurate Fractional-Order Systems

Algorithms, 2023
In this paper, the possibilities of expressing the natural response of a linear commensurate fractional-order system (FOS) as a linear combination of basis functions are analyzed.
Dalibor Biolek, Viera Biolková, Zdeněk Kolka, Zdeněk Biolek   +3 more
doaj   +1 more source

Mode identification by eigensystem realization algorithm through virtual frequency response function

Structural Control & Health Monitoring, 2019
Mode identification in civil engineering uses ambient excitation response, where the excitation is assumed to be stationary white noise. However, practical engineering conditions cannot satisfy this assumption of ideal excitation.
C. Qu, T. Yi, Hongnan Li
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Critical response of a single-degree-of-freedom system with bilinear hysteresis and viscous damping under triple impulse

Frontiers in Built Environment
A triple impulse is used as a mathematical model of forward-directivity inputs, which are fault-normal components of near-fault earthquake ground motions. In this paper, two types of the triple impulse input are employed.
Kotaro Kojima, Izuru Takewaki
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Investigation of the Physical Mechanism of Acoustic Attenuation in Viscous Isotropic Solids

Micromachines, 2022
The traditional acoustic attenuation coefficient is derived from an analogy of the attenuation of an electromagnetic wave propagating inside a non-ideal medium, featuring only the attenuation of wave propagation. Nonetheless, the particles inside viscous
Lin Fa, Lili Li, Hong Gong, Wenhui Chen, Jing Jiang, Guoqiang You, Jifeng Liang, Yandong Zhang, Meishan Zhao   +8 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

EFFECT OF SHOCKS OF AGRICULTURAL TERMS OF TRADE (TOT) ON SOME AGRICULTURAL INDICATORS IN IRAQ FOR THE PERIOD (1990 - 2019)

The Iraqi Journal of Agricultural science
This study aimed to investigate the impact of agricultural TOT shocks and the strength of their effects on some indicators of the agricultural sector. The research uses VAR, Variance decomposition and IRF approaches.
AlAttabi, H. A., B. H. AlBadri
doaj   +1 more source