This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Multimodal Autonomic Biomarkers Predict Phenoconversion in Pure Autonomic Failure
ABSTRACT Background Pure autonomic failure (PAF) presents with autonomic failure without other neurological features. A third develop central neurological features, fulfilling criteria for multiple system atrophy (MSA) and Lewy body diseases (LBD), including Parkinson's disease and Dementia with Lewy bodies.
S. Koay +12 more
wiley +1 more source
Dynamic of a nonautonomous two-species impulsive competitive system with infinite delays
In this paper, we consider a nonautonomous two-species impulsive competitive system with infinite delays. By the impulsive comparison theorem and some mathematical analysis, we investigate the permanence, extinction and global attractivity of the system,
He Mengxin, Li Zhong, Chen Fengde
doaj +1 more source
ICU‐EEG Pattern Detection by a Convolutional Neural Network
ABSTRACT Objective Patients in the intensive care unit (ICU) often require continuous EEG (cEEG) monitoring due to the high risk of seizures and rhythmic and periodic patterns (RPPs). However, interpreting cEEG in real time is resource‐intensive and heavily relies on specialized expertise, which is not always available.
Giulio Degano +5 more
wiley +1 more source
The observational evidence pertinent to possible kick mechanisms in neutron stars [PDF]
We examine available observations on pulsars for evidence pertaining to mechanisms proposed to explain the origin of their velocities. We find that mechanisms predicting a correlation between the rotation axis and the pulsar velocity are ruled out. Also,
Deshpande, A. A. +2 more
core +3 more sources
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald +74 more
wiley +1 more source
Muscle-Specific Effective Mechanical Advantage and Joint Impulse in Weightlifting [PDF]
Lifting greater loads during weightlifting exercises may theoretically be achieved through increasing the magnitudes of net joint impulses or manipulating the joints’ effective mechanical advantage (EMA).
Harris, Chad, Kipp, Kristof
core +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Periodic solutions for neutral functional differential equations with impulses on time scales
Let $mathbb{T}$ be a periodic time scale. We use Krasnoselskii's fixed point theorem to show that the neutral functional differential equation with impulses $$displaylines{ x^{Delta}(t)=-A(t)x^sigma(t)+g^Delta(t,x(t-h(t)))+f(t,x(t),x(t-h(t))),quad ...
Yongkun Li, Xiaoyan Dou, Jianwen Zhou
doaj
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski +13 more
wiley +1 more source

