Results 61 to 70 of about 655,823 (403)

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

open access: yesMolecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Adaptive Pinning Synchronization of Fractional Complex Networks with Impulses and Reaction–Diffusion Terms

open access: yesMathematics, 2019
In this paper, a class of fractional complex networks with impulses and reaction−diffusion terms is introduced and studied. Meanwhile, a class of more general network structures is considered, which consists of an instant communication topology and
Xudong Hai   +3 more
doaj   +1 more source

The observational evidence pertinent to possible kick mechanisms in neutron stars [PDF]

open access: yes, 1999
We examine available observations on pulsars for evidence pertaining to mechanisms proposed to explain the origin of their velocities. We find that mechanisms predicting a correlation between the rotation axis and the pulsar velocity are ruled out. Also,
Deshpande, A. A.   +2 more
core   +3 more sources

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Electronic device increases threshold sensitivity and removes noise from FM communications receiver [PDF]

open access: yes, 1971
Threshold extension device connected between demodulator output and filter output minimizes clicking noise. Device consists of click-eliminating signal transfer channel with follow-and-hold circuit and detector for sensing click impulses.
Conrad, W. M., Loch, F. J.
core   +1 more source

Averaging approach to phase coherence of uncoupled limit-cycle oscillators receiving common random impulses

open access: yes, 2008
Populations of uncoupled limit-cycle oscillators receiving common random impulses show various types of phase-coherent states, which are characterized by the distribution of phase differences between pairs of oscillators.
A. Lasota   +10 more
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Impulsive Memristive Cohen–Grossberg Neural Networks Modeled by Short Term Generalized Proportional Caputo Fractional Derivative and Synchronization Analysis

open access: yesMathematics, 2022
The synchronization problem for impulsive fractional-order Cohen–Grossberg neural networks with generalized proportional Caputo fractional derivatives with changeable lower limit at any point of impulse is studied.
Ravi Agarwal, Snezhana Hristova
doaj   +1 more source

Integral Input-to-State Stability of Nonlinear Time-Delay Systems with Delay-Dependent Impulse Effects

open access: yes, 2020
This paper studies integral input-to-state stability (iISS) of nonlinear impulsive systems with time-delay in both the continuous dynamics and the impulses. Several iISS results are established by using the method of Lyapunov-Krasovskii functionals.
Zhang, Kexue
core  

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