Results 101 to 110 of about 64,196 (265)

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

Epilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen, Vivian W. Y. Liao, Tomasz S. Mieszczanek, Anne V. Jakobsen, Elena Gardella, Kern Olofsson, Marina Nikanorova, Allan Bayat, Sebastian Ortiz, Sarah Weckhuysen, Cecilie Johannessen Landmark, Orrin Devinsky, Mary Chebib, Philip K. Ahring, Guido Rubboli, Rikke S. Møller   +15 more
wiley   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

An SSI‐Informed Design for Tuned Mass Dampers With Small‐to‐Large Mass Ratios

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Tuned Mass Dampers (TMDs) are used to mitigate structural vibrations induced by seismic or wind excitation, by tuning the device to the system's dominant resonant frequencies. However, the TMD effectiveness can be undermined by soil‐structure interaction, which can lead to elongation of the vibration periods and to combined translational ...
Davide Noè Gorini, Pasquale Roberto Marrazzo, Elide Nastri, Rosario Montuori   +3 more
wiley   +1 more source

Weak‐Story Mitigation and Drift Redistribution in Moment‐Resisting Frames Using Stepping Rocking Walls

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT This study investigates the seismic response of moment‐resisting frames retrofitted with a stepping rocking wall, with emphasis on weak‐story mitigation and residual drift reduction under both ordinary and pulse‐like ground motions. Nonlinear response‐history analyses are conducted on 9‐story and 20‐story SAC Los Angeles frames.
Mehrdad Aghagholizadeh
wiley   +1 more source

Impact of COVID‐19 Lockdown on Psychopathology at the Onset of Eating Disorders

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Previous research has shown that the COVID‐19 pandemic worsened eating‐disorder (ED) symptoms, but most studies have focused on inpatients and compared only two periods: pre‐COVID and the period following the pandemic's onset. Outpatient populations, particularly those with binge eating disorder (BED) and other specified feeding or ...
Elvira Anna Carbone, Cristiano Dani, Matteo Geraci, Alessia Romeo, Ana Jiménez‐Peinado, Marianna Rania, Enrico Lodovici, Valentina Zofia Cordasco, Emanuele Cassioli, Eleonora Rossi, Livio Tarchi, Valdo Ricca, Giovanni Castellini, Cristina Segura‐Garcia   +13 more
wiley   +1 more source

Association Between Trauma, Impulsivity, and Functioning in Suicide Attempters

Behavioral Sciences
Suicide is a significant public health concern associated with multiple risk factors. Among these factors, a history of trauma and impulsivity has recently received particular attention.
Paula Jhoana Escobedo-Aedo, Alejandro Porras-Segovia, Maria Luisa Barrigón, Philippe Courtet, Jorge López-Castroman, Enrique Baca-Garcia   +5 more
doaj   +1 more source

Sleep Health in Bulimia Nervosa: A Systematic Review

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Research on sleep in bulimia nervosa (BN) is methodologically varied and yields inconsistent findings. This review synthesised BN‐sleep studies and examined whether comorbid mood disorders contribute to sleep disturbance. Method PsycINFO, Medline (Ovid), and Scopus were searched for English or French quantitative studies comparing ...
Samantha Kenny, Malka Hershon, Linda Booij, Rebecca Burdayron, Marie‐Hélène Pennestri   +4 more
wiley   +1 more source

Decentralized Federated Learning for Wind Turbine Bearing Prognostics Under Data Scarcity and Statistical Heterogeneity

Energy Science &Engineering, EarlyView.
This paper proposes a decentralized peer‐to‐peer federated learning framework for wind turbine bearing remaining useful life prediction, introducing a virtual client paradigm in which statistical health indicators serve as independent feature‐level clients—enabling privacy‐preserving collaborative prognostics from a single physical asset under ...
Jihene Sidhom, Lotfi Saidi, Eric Bechhoefer   +2 more
wiley   +1 more source

Fast Calculation for the Flow and Heat Transfer of Tempered Fractional Maxwell Viscoelastic Fluid

International Journal for Numerical Methods in Fluids, EarlyView.
This study develops a tempered fractional Maxwell model to simulate unsteady thermal flow in viscoelastic fluids, capturing key rheological behaviors. A fast SOE‐based algorithm is proposed to improve the computational efficiency of the numerical scheme. Results reveal how key parameters influence fluid motion and heat transfer, demonstrating the model'
Yi Liu, Mochen Jiang, Libo Feng
wiley   +1 more source

Recent advances in multifunctional soft robots: A materials–structures–systems co‐design perspective for synergistic integration

FlexMat, EarlyView.
Abstract Soft robots, engineered from highly compliant materials, offer superior adaptability and safety in unstructured environments compared to their rigid counterparts. Recent advancements, fueled by bio‐inspiration and material programmability, have led to the rapid co‐evolution of their core modules: actuation, sensing, protection, energy, and ...
Qiulei Liu, Zicao Peng, Chong Sun, Haitao Yang   +3 more
wiley   +1 more source