Results 31 to 40 of about 473,642 (344)

Conditional knock out of transcription factor CTCF in excitatory neurons induces cognitive deficiency

Molecular Brain, 2021
CCCTC-binding factor (CTCF) is a transcription factor that is involved in organizing chromatin structure. A reduction of CTCF expression is known to develop distinct clinical features.
Dong Il Choi, Myeongwon Kim, Somi Kim, Nam-Kyung Yu, Chuljung Kwak, Hyunhyo Seo, Kyungmin Lee, Bong-Kiun Kaang   +7 more
doaj   +1 more source

Robust Bidirectional Gate Driver on Array Based on Indium Gallium Zinc Oxide Thin-Film Transistor for In-Cell Touch Displays

IEEE Journal of the Electron Devices Society
In this paper, we propose a bidirectional gate driver on array (GOA) circuit design based on indium gallium zinc oxide (IGZO) thin-film transistor (TFT) to support time-division driving method (TDDM) for in-cell touch displays.
Liufei Zhou, Fuchao He, Xiaojun Guo, Haihong Wang, Mingxin Wang, Yuning Zhang, Baoping Wang   +6 more
doaj   +1 more source

The current distribution in an electrochemical cell. Part VII. Concluding remarks [PDF]

Journal of the Serbian Chemical Society, 2002
Anew method for the determination of the ability of an electrolyte to distribute uniformly current density in an electrochemical cell is proposed. It is based on the comparison of the current in cells in which the electrode edges touch the cell side ...
Popov Konstantin I., Pešić S.M., Živković Predrag M.   +2 more
doaj   +1 more source

Horizontal transfer of antibiotic resistance genes on abiotic touch surfaces: implications for public health

, 2012
Horizontal gene transfer (HGT) is largely responsible for increasing incidence of antibiotic-resistant infections worldwide. Whilst studies have focussed on HGT in vivo, this work investigates whether the ability of pathogens to persist in the ...
Bonnin, Bonomo, Boyce, Bush, Cohen Stuart, Espírito Santo, Goren, Guet-Revillet, Hong, Jacoby, Keevil, Kramer, Kruse, Kumarasamy, McGann, Mehtar, Nordmann, Nordmann, Noyce, Noyce, Noyce, Overdevest, O’Keefe, Potron, Schmidt, Schmidt, Tuon, Walsh, Warnes, Warnes, Warnes, Weaver, Weaver, Wilks, Wilks, Woodford, Woodford, World Health Organization, Yong   +38 more
core   +1 more source

The cellular and synaptic architecture of the mechanosensory dorsal horn [PDF]

, 2017
The deep dorsal horn is a poorly characterized spinal cord region implicated in processing low-threshold mechanoreceptor (LTMR) information. We report an array of mouse genetic tools for defining neuronal components and functions of the dorsal horn LTMR ...
Abraira, Alexis A. Toliver, Amanda L. Zimmerman, Anda M. Chirila, Andersen, Bai, Bourane, Bryan J. Song, Burgess, Casale, Connie Tsan, Coutaud, Dani, David D. Ginty, David I. Hughes, Du Beau, Emily D. Kuehn, Ferreira, Garcia-Segura, Gjerstad, Gong, Gorski, Graham, Graham, Grudt, Gutierrez-Mecinas, Hasegawa, Horch, Hughes, Ippolito, Jessica Hoynoski, Johnson, Justin Zhuo, Kaiser, Karleena A. Bashista, Kieran A. Boyle, Kim, Laing, Laura Kus, Lauren L. Orefice, Laurent, Li, Ling Bai, Liu, Liu, Lorenzo, Luo, Mark W. Springel, Masahiko Watanabe, Masland, Michael Rutlin, Nakatsuka, Nathaniel Heintz, Niederkofler, Olausson, Orefice, Otazu, Owens, Punnakkal, Rajković, Ralston, Rozell, Rustioni, Rutlin, Sacha B. Nelson, Saunders, Seal, Sieber, Susan M. Dymecki, Tamamaki, Taniguchi, Thomas G. O'Neill, Todd, Todd, Torsney, Uesaka, Valtschanoff, Vera Niederkofler, Victoria E. Abraira, Yasaka, Zimmerman   +80 more
core   +1 more source

Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy [PDF]

, 1984
Post-transplant lymphomas or other lymphoproliferative lesions, which were usually associated with Epstein-Barr virus infections, developed in 8, 4, 3, and 2 recipients, respectively, of cadaveric kidney, liver, heart, and heart-lung homografts ...
Atchison, RW, Bahnson, HT, Griffith, BP, Hakala, TR, Hardesty, RL, Ho, M, Iwatsuki, S, Jaffe, R, Nalesnik, MA, Porter, KA, Rosenthal, JT, Shaw, BW, Starzl, TE   +12 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Analysis of red autofluorescence (650-670nm) in epidermal cell populations and its potential for distinguishing contributors to 'touch' biological samples [version 1; referees: 2 approved]

F1000Research, 2016
Interpretation of touch DNA mixtures poses a significant challenge for forensic caseworking laboratories.  Front end techniques that facilitate separation of contributor cell populations before DNA extraction are a way to circumvent this problem.
Cristina E. Stanciu, M. Katherine Philpott, Eduardo E. Bustamante, Ye Jin Kwon, Christopher J. Ehrhardt   +4 more
doaj   +1 more source

Transcriptional Programming of Human Mechanosensory Neuron Subtypes from Pluripotent Stem Cells

Cell Reports, 2020
Summary: Efficient and homogeneous in vitro generation of peripheral sensory neurons may provide a framework for novel drug screening platforms and disease models of touch and pain.
Alec R. Nickolls, Michelle M. Lee, David F. Espinoza, Marcin Szczot, Ruby M. Lam, Qi Wang, Jeanette Beers, Jizhong Zou, Minh Q. Nguyen, Hans J. Solinski, Aisha A. AlJanahi, Kory R. Johnson, Michael E. Ward, Alexander T. Chesler, Carsten G. Bönnemann   +14 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source