Results 51 to 60 of about 475,711 (295)

Highly efficient optogenetic cell ablation in C. elegans using membrane-targeted miniSOG. [PDF]

open access: yes, 2016
The genetically encoded photosensitizer miniSOG (mini Singlet Oxygen Generator) can be used to kill cells in C. elegans. miniSOG generates the reactive oxygen species (ROS) singlet oxygen after illumination with blue light.
Chisholm, Andrew D, Xu, Suhong
core   +1 more source

Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors [PDF]

open access: yesNature, 2014
Touch submodalities, such as flutter and pressure, are mediated by somatosensory afferents whose terminal specializations extract tactile features and encode them as action potential trains with unique activity patterns. Whether non-neuronal cells tune touch receptors through active or passive mechanisms is debated. Terminal specializations are thought
Maksimovic, Srdjan   +10 more
openaire   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

The second touch hypothesis: T cell activation, homing and polarization [v1; ref status: indexed, http://f1000r.es/2w7]

open access: yesF1000Research, 2014
The second touch hypothesis states that T cell activation, proliferation, induction of homing receptors and polarization are distinguishable and, at least in part, sequential. The second touch hypothesis maintains that full T cell polarization requires T
Klaus Ley
doaj   +1 more source

Dermal appendage-dependent patterning of zebrafish atoh1a+ Merkel cells

open access: yeseLife, 2023
Touch system function requires precise interactions between specialized skin cells and somatosensory axons, as exemplified by the vertebrate mechanosensory Merkel cell-neurite complex.
Tanya L Brown   +9 more
doaj   +1 more source

Co-option of epidermal cells enables touch sensing

open access: yesNature Cell Biology, 2023
AbstractThe epidermis is equipped with specialized mechanosensory organs that enable the detection of tactile stimuli. Here, by examining the differentiation of the tactile bristles, mechanosensory organs decorating the Drosophila adult epidermis, we show that neighbouring epidermal cells are essential for touch perception.
Mangione, Federica   +6 more
openaire   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Analysis of cutaneous MRGPRD free nerve endings and C-LTMRs transcriptomes by RNA-sequencing

open access: yesGenomics Data, 2015
The skin is the largest sensory organ that is densely innervated by highly specialized sensory neurons allowing the detection of a wide range of stimulations including light touch, temperature, itch and pain.
Ana Reynders, Aziz Moqrich
doaj   +1 more source

Tactor devices : using tactile interface designs for mobile digital appliances : a practice-based research thesis for the fulfilment of a Master of Design degree, College of Design, Fine Arts, and Music, Massey University, Wellington [PDF]

open access: yes, 2003
This Thesis focuses the potential of communication interfaces that use tactors (tactile actuators) to improve user interactions with mobile digital devices which are currently based on audio and visual technologies.
Mainz, Till
core  

Electrorotation of a pair of spherical particles

open access: yes, 2001
We present a theoretical study of electrorotation (ER) of two spherical particles under the action of a rotating electric field. When the two particles approach and finally touch, the mutual polarization interaction between the particles leads to a ...
B. R. Djordjevic   +15 more
core   +3 more sources

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