Results 81 to 90 of about 229,616 (309)

Comparison of return of spontaneous circulation prediction scores in patients with cardiac arrest during ambulance transport

BMC Emergency Medicine
Background Cardiac arrest during ambulance transport is a complex situation that has features of both in-hospital cardiac arrest (IHCA) and out-of-hospital cardiac arrest (OHCA) but lacks a clear classification.
Neslihan Ergün Süzer, Gülbin Aydoğdu Umaç, Süleyman Alpar, Sarper Yılmaz   +3 more
doaj   +1 more source

Effect of a strategy of a supraglottic airway device vs tracheal intubation during out-of-hospital cardiac arrest on functional outcome [PDF]

, 2018
Importance The optimal approach to airway management during out-of-hospital cardiac arrest is unknown. Objective To determine whether a supraglottic airway device (SGA) is superior to tracheal intubation (TI) as the initial advanced airway ...
Benger, Jonathan R., Black, Sarah, Brett, Stephen J., Clout, Madeleine, Kirby, Kim, Lazaroo, Michelle J., Nolan, Jerry P., Reeves, Barnaby C., Robinson, Maria, Rogers, Chris A., Scott, Lauren J., Smartt, Helena, South, Adrian, Stokes, Elizabeth A., Taylor, Jodi, Thomas, Matthew, Voss, Sarah, Wordsworth, Sarah   +17 more
core   +4 more sources

Update: Focus in-hospital maternal cardiac arrest

Journal of Gynecology Obstetrics and Human Reproduction, 2019
The incidence of maternal cardiac arrest ranges from 1/55,000 to 1/12,000 births. It is due most frequently to cardiovascular, hemorrhagic, and anesthesia-related causes, as well as to amniotic fluid embolism. The basic principles of resuscitation remain applicable in this situation, but the physiological modifications of pregnancy must be taken into ...
Fischer, C., Bonnet, M.P., Girault, A., Le Ray, C.   +3 more
openaire   +5 more sources

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

A retrospective study of in‐hospital cardiac arrest

Acute Medicine & Surgery, 2016
Aim In‐hospital cardiac arrest is an important issue in health care today. Data regarding in‐hospital cardiac arrest in Japan is limited. In Australia and the USA, the Rapid Response System has been implemented in many institutions and data regarding in ...
Shinsuke Fujiwara, Tomotaka Koike, Megumi Moriyasu, Masashi Nakagawa, Kazuaki Atagi, Alan K. Lefor, Shigeki Fujitani, IHCA study group   +7 more
doaj   +1 more source

XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss

Advanced Science, EarlyView.
Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan, Yuhua Zhang, Jiawei Du, Yongjun Zhu, Wei Cao, Yongjie Wei, Han Wu, Shiyu Qiu, Shiyi Pan, Lian Chen, Pingping Liang, Renjie Chai, Jianming Yang, Qiaojun Fang   +13 more
wiley   +1 more source

The unrealistic expectations of CPR success: a comparative public survey of Saudi Arabia and the United States

Saudi Journal of Emergency Medicine
Background: Success rates of cardiopulmonary resuscitation (CPR) in in-hospital cardiac arrest (INCA) and out-of-hospital cardiac arrest OOHCA is reported to be 15% and 3%, respectively. However, people in the general population have high and unrealistic
Thamer Khalid Zoghbi, Mohammed Abdulaziz AlAryni, Anas Fouad Hamam   +2 more
doaj   +1 more source

Adenylyl Cyclase 8 in Dorsal CA1 Neurons Prevents Depressive‐Like Behaviors by Maintaining Neuronal Excitability and Glutamatergic Neurotransmission Through TIP39‐PTH2R Signaling

Advanced Science, EarlyView.
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu, Jia‐Rui Bi, Zong‐Yan Yu, Meng Tian, Zhi‐Yue Chen, Ran Wei, Miao‐Miao Wang, Hai‐Wei Zha, Yu‐Qing Zhang, Hong‐Jing Wang, Bang‐You Qiang, Shuang‐Shuang Sun, Xiao‐Juan Zhu, Wen‐Bing Chen, Dong Sun   +14 more
wiley   +1 more source

The German Resuscitation Registry – Epidemiological data for out-of-hospital and in-hospital cardiac arrest

Resuscitation Plus
Introduction: The German Resuscitation Registry was started in 2007 and collects data on out-of-hospital as well as in-hospital cardiac arrest and resuscitation. It has collected more than 400.000 datasets till today.
Jan Wnent, Jan-Thorsten Gräsner, Matthias Fischer, Alexandra Ramshorn-Zimmer, Andreas Bohn, Berthold Bein, Stephan Seewald   +6 more
doaj   +1 more source