Results 61 to 70 of about 115,019,574 (294)

Explicit memory schemes for evolutionary algorithms in dynamic environments [PDF]

open access: yes, 2007
Copyright @ 2007 Springer-VerlagProblem optimization in dynamic environments has atrracted a growing interest from the evolutionary computation community in reccent years due to its importance in real world optimization problems.
Yang, S   +2 more
core   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

CIDAN-XE: Computing in DRAM with Artificial Neurons

open access: yesFrontiers in Electronics, 2022
This paper presents a DRAM-based processing-in-memory (PIM) architecture, called CIDAN-XE. It contains a novel computing unit called the neuron processing element (NPE).
Gian Singh   +3 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Matrix Mapping on Crossbar Memory Arrays with Resistive Interconnects and Its Use in In-Memory Compression of Biosignals

open access: yesMicromachines, 2019
Recent advances in nanoscale resistive memory devices offer promising opportunities for in-memory computing with their capability of simultaneous information storage and processing.
Yoon Kyeung Lee   +6 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Exploring memory in email refinding [PDF]

open access: yes, 2008
Human memory plays an important role in personal information management (PIM). Several scholars have noted that people refind information based on what they remember and it has been shown that people adapt their management strategies to compensate for ...
Baillie, M.   +5 more
core   +1 more source

Stateful In‐Memory Logic System and Its Practical Implementation in a TaOx‐Based Bipolar‐Type Memristive Crossbar Array

open access: yesAdvanced Intelligent Systems, 2020
Memristive stateful logic enables energy‐ and cost‐efficient in‐memory computing, which is desirable for edge computing in the coming Internet of Things  (IoT) era.
Young Seok Kim   +8 more
doaj   +1 more source

Self-rectifying resistive memory in passive crossbar arrays

open access: yesNature Communications, 2021
Memory-centric computing refers to computing designs where the memory, rather than the processor is central in the architecture. Here, the authors demonstrate a self-rectifying resistive memory cell that exhibits impressive endurance, and low power ...
Kanghyeok Jeon   +7 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

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