Results 91 to 100 of about 115,577,048 (299)
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
The role of time in the relation between perceived job insecurity and perceived job performance
WORK: A Journal of Prevention, Assessment & Rehabilitation, 2020 BACKGROUND: Insufficient evidence exists that can explain two conflicting views (i.e. positive and negative relationship) regarding the effect of job insecurity on job performance. OBJECTIVE: To investigate the importance of time in ...
openaire +4 more sources
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
The purpose of this study is to determine the role of job commitment in the effect of positive psychological capital on individual job performance. For this purpose, the convenience sampling method was used to collect data from senior managers of 82 enterprises in the manufacturing sector in Kayseri.
Oğuzhan, Yavuz Sezer, Yücekaya, Polat
openaire +3 more sources
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
, 2023 The study was an assessment of educational qualification and job position satisfaction as correlate of employees’ job performance in Eco Bank PLC, Calabar, Cross River State, Nigeria.
Ekpenyong Bassey Obo (15465629)
core +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Frontiers in Psychology, 2017 The present study aims to connect more the I/O and the decision-making psychological domains, by showing how some common components across jobs interfere with decision-making and affecting performance.
Andrea Ceschi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Impact of Job Involvement on In-Role Job Performance and Organizational Citizenship Behaviour [PDF]
Journal of Behavioral and Applied Management, 2008 This study examines the impact of job involvement on the self-report measures of inrole job performance and organizational citizenship behaviour. The results of this study revealed that job involvement was positively correlated with both in-role job performance (r = 0.30, p<0.01) and OCB (r = 0 ...
openaire +1 more source