Results 111 to 120 of about 115,018,060 (255)

Advances in 3D Bioprinting for Breast Cancer Modeling: Tumor Microenvironment, Metastasis, and Drug Screening

open access: yesAdvanced Healthcare Materials, EarlyView.
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu   +7 more
wiley   +1 more source

Urea Delays High-Temperature Crosslinking of Polyacrylamide for In Situ Preparation of an Organic/Inorganic Composite Gel

open access: yes
To address the rapid crosslinking reaction and short stability duration of polyacrylamide gel under high salinity and temperature conditions, this paper proposes utilizing urea to delay the nucleophilic substitution crosslinking reaction among ...
Junlong Li   +5 more
core   +1 more source

Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez   +8 more
wiley   +1 more source

Improved corneal bioavailability of ofloxacin: biodegradable microsphere-loaded ion-activated in situ gel delivery system

open access: yesDrug Design, Development and Therapy, 2015
Elshaimaa G Sayed,1 Amal K Hussein,1 Khaled A Khaled,1 Osama AA Ahmed1,2 1Department of Pharmaceutical Technology, Faculty of Pharmacy, Minia University, Minia, Egypt; 2Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King  ...
Sayed EG   +3 more
doaj  

Effect of Pluronic F127 Concentration on Gelling Temperature and other Parameters of Lomustine Mucoadhesive In-Situ Gel

open access: yesIraqi Journal of Pharmaceutical Sciences
Pluronic F127 is one of the widely used thermoreversible gelling agent, and used in sol-to-gel transformation. It has been used to localize drug delivery such as nose-to-brain delivery which allows the direct targeting of drug molecules bypassing the ...
Maryam H. Alaayedi   +1 more
doaj   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

Editorial : In situ, revue de l’Inventaire général [PDF]

open access: yes, 2012
Figure 1 Vierge à l’Enfant, statue en terre cuite entourée de François Lasa, photographe et de François Le Bœuf, chercheur, service régional de l’Inventaire en Pays-de-la-Loire Phot. Inv. F.
Verdier, Hélène
core  

Ocular in situ gel: An overview

open access: yes, 2019
Eye is the most sensitive organ of the body. Designing of ocular drug delivery system is the  most challenging field for pharmaceutical scientists as less than 5% of administered drug enters the eye due to the complicated anatomical structure of the
Khan, Nisar Ahmad, Majeed, Asmat
core   +1 more source

Azobenzene's Cross‐Scale Optics and Photonics: Molecular Photoswitching, Mesoscopic Material Motions, and Adaptive Devices

open access: yesAdvanced Materials, EarlyView.
Azobenzene photoswitches translate molecular‐scale E/Z photoisomerization into macroscopic material responses and device‐level photonic functions. This Review highlights how azobenzene research has evolved from molecular photochemistry to photoalignment, mass migration, photomechanics, and heat release, ultimately enabling holography, reconfigurable ...
Heeju Son   +20 more
wiley   +1 more source

Gel-Like Calcium Carbonate Precursors Observed by in situ AFM

open access: yes, 2016
The debate about crystallization processes is still ongoing and nonclassical crystallization mechanisms attract more and more attention. This work indicates that polymer induced liquid precursor (PILP) phases play a role for nonclassical calcium ...
Stefan L. P. Wolf (3592049)   +3 more
core   +1 more source

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