A Bibliometric Analysis and Systematic Review of Research Advances in In Situ Gel Drug Delivery Systems from 2003 to 2023 [PDF]
Objective: We aimed analyze research trends in in situ gel drug delivery systems. Methods: Studies from 2003 to 2023 were systematically obtained from the Web of Science database and analyzed using VOSviewer software to evaluate publication trends ...
Huanyu Zhou, Mingqing Yuan, Tao Zhang
doaj +2 more sources
Development of Carvedilol Nanoformulation-Loaded Poloxamer-Based In Situ Gel for the Management of Glaucoma [PDF]
The objective of the current study was to fabricate a thermosensitive in situ gelling system for the ocular delivery of carvedilol-loaded spanlastics (CRV-SPLs).
Bjad K. Almutairy +2 more
doaj +2 more sources
Disulfiram thermosensitive in-situ gel based on solid dispersion for cataract
To improve the corneal permeability and water-solubility of disulfiram (DSF), which is an ocular drug for cataract, P188 was selected as a matrix to prepare solid dispersion of DSF (DSFSD) by hot melt method.
Chunjuan Zhang +5 more
doaj +3 more sources
This study aimed to develop syringeable in-situ curcumin (cur) gel for the treatment of periodontal pockets as well as to evaluate the clinical efficacy of Cur in-situ gel formulation.
Maha M. A. Nasra +3 more
doaj +2 more sources
Evaluation of in-situ gel-forming eye drop containing bacteriophage against Pseudomonas aeruginosa keratoconjunctivitis in vivo [PDF]
Introduction: Eradication of Pseudomonas aeruginosa has become increasingly difficult due to its remarkable capacity to resist antibiotics. Bacteriophages have been suggested as an alternative treatment for bacterial infections.
Golnar Rahimzadeh +10 more
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Study on the nasal drug delivery system of PPX microcapsules
Pramipexole hydrochloride (PPX) is a dopamine receptor agonist for the treatment of Parkinson's disease. It does not penetrate easily into the brain due to the presence of the blood-brain barrier (BBB), which hinders the treatment of the disease.
in situ thermosensitive gel Lin Ma +4 more
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Development of In Situ Gel Containing Phytoconstituents for the Treatment of Mouth Ulcers
An ulcer that develops on the mucosal surface of the oral cavity is known as a mouth ulcer, also known as an oral ulcer or a mucosal ulcer. A mucus membrane ulcer is an open sore that is distinguished by the removal of inflammatory dead tissue.
Kevinkumar Garala, Parag Rabara
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Frovatriptan succinate intranasal delivery for brain targeting – in vivo study.
Muco-adhesive gel formulations are advantageous in extending the stay at the nasal absorption place, promoting drug absorption. Frovatriptan succinate (FVT) exhibits a 35% oral bioavailability and undergoes hepatic metabolism, making it a viable ...
Mohammed layth hamzah +1 more
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Comparative Study of In Situ Gel Formulation Based on the Physico-Chemical Aspect: Systematic Review [PDF]
Iyan Sopyan +2 more
exaly +2 more sources
This study aims to develop a thermosensitive mucoadhesive periodontal in situ gel of secnidazole for local release of drug for treatment of periodontitis, in order to increase the drug residence time and to increase patient compliance while lowering the
Dheyaa A Raheema, Hanan Jalal Kassab
doaj +1 more source

