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A Bibliometric Analysis and Systematic Review of Research Advances in In Situ Gel Drug Delivery Systems from 2003 to 2023 [PDF]

open access: yesPharmaceutics
Objective: We aimed analyze research trends in in situ gel drug delivery systems. Methods: Studies from 2003 to 2023 were systematically obtained from the Web of Science database and analyzed using VOSviewer software to evaluate publication trends ...
Huanyu Zhou, Mingqing Yuan, Tao Zhang
doaj   +2 more sources

Development of Carvedilol Nanoformulation-Loaded Poloxamer-Based In Situ Gel for the Management of Glaucoma [PDF]

open access: yesGels, 2023
The objective of the current study was to fabricate a thermosensitive in situ gelling system for the ocular delivery of carvedilol-loaded spanlastics (CRV-SPLs).
Bjad K. Almutairy   +2 more
doaj   +2 more sources

Disulfiram thermosensitive in-situ gel based on solid dispersion for cataract

open access: yesAsian Journal of Pharmaceutical Sciences, 2018
To improve the corneal permeability and water-solubility of disulfiram (DSF), which is an ocular drug for cataract, P188 was selected as a matrix to prepare solid dispersion of DSF (DSFSD) by hot melt method.
Chunjuan Zhang   +5 more
doaj   +3 more sources

Formulation, in-vitro characterization and clinical evaluation of curcumin in-situ gel for treatment of periodontitis

open access: yesDrug Delivery, 2017
This study aimed to develop syringeable in-situ curcumin (cur) gel for the treatment of periodontal pockets as well as to evaluate the clinical efficacy of Cur in-situ gel formulation.
Maha M. A. Nasra   +3 more
doaj   +2 more sources

Evaluation of in-situ gel-forming eye drop containing bacteriophage against Pseudomonas aeruginosa keratoconjunctivitis in vivo [PDF]

open access: yesBioImpacts, 2021
Introduction: Eradication of Pseudomonas aeruginosa has become increasingly difficult due to its remarkable capacity to resist antibiotics. Bacteriophages have been suggested as an alternative treatment for bacterial infections.
Golnar Rahimzadeh   +10 more
doaj   +1 more source

Study on the nasal drug delivery system of PPX microcapsules

open access: yesPakistan Journal of Pharmaceutical Sciences, 2022
Pramipexole hydrochloride (PPX) is a dopamine receptor agonist for the treatment of Parkinson's disease. It does not penetrate easily into the brain due to the presence of the blood-brain barrier (BBB), which hinders the treatment of the disease.
in situ thermosensitive gel Lin Ma   +4 more
doaj   +1 more source

Development of In Situ Gel Containing Phytoconstituents for the Treatment of Mouth Ulcers

open access: yesMedical Sciences Forum, 2022
An ulcer that develops on the mucosal surface of the oral cavity is known as a mouth ulcer, also known as an oral ulcer or a mucosal ulcer. A mucus membrane ulcer is an open sore that is distinguished by the removal of inflammatory dead tissue.
Kevinkumar Garala, Parag Rabara
doaj   +1 more source

Frovatriptan succinate intranasal delivery for brain targeting – in vivo study.‎

open access: yesThe Iraqi Journal of Veterinary Medicine, 2023
Muco-adhesive gel formulations are advantageous in extending the stay at the nasal ‎absorption place, promoting drug absorption. Frovatriptan succinate (FVT) exhibits a 35% ‎oral bioavailability and undergoes hepatic metabolism, making it a viable ...
Mohammed layth hamzah   +1 more
doaj   +1 more source

Preparation and in-vitro Evaluation of Secnidazole as Periodontal In-situ Gel for Treatment of Periodontal Disease

open access: yesIraqi Journal of Pharmaceutical Sciences, 2022
This study aims to develop a thermosensitive mucoadhesive periodontal in situ gel of secnidazole for local release of drug for treatment of periodontitis, in order to increase the drug residence time and to increase patient compliance while lowering the
Dheyaa A Raheema, Hanan Jalal Kassab
doaj   +1 more source

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