Results 31 to 40 of about 115,018,110 (301)

A REVIEW ON OCULAR IN SITU GEL

International Journal of Pharmaceutical Sciences and Medicine, 2022
Ophthalmic drug delivery presents major challenges for pharmaceutical and medicinal sciences. New ocular drug delivery forms are various; they included in situ gelling systems, liposome’s, nanoparticles, noisome, nanoemulsions and microemulsions. They are suitable for hydrophilic or lipophilic drugs, have the capacity of targeting a specific site and ...
Saini Abhishek, Pawar Rajat, Dubey P.K
openaire   +1 more source

Intranasal Delivery of Darunavir-Loaded Mucoadhesive In Situ Gel: Experimental Design, In Vitro Evaluation, and Pharmacokinetic Studies

, 2022
The clinical efficacy of antiretroviral therapy in NeuroAIDS is primarily limited by the low perfusion of the drug to the brain. The objective of the current investigation was to design and develop an in situ mucoadhesive gel loaded with darunavir to ...
Bandar Aldhubiab, Anroop B. Nair, Nair, Anroop B., Chaudhary, Sunita, Sreeharsha, Nagaraja, Hiral Shah, Jacob, Shery, Vivek Mewada, Nagaraja Sreeharsha, Shah, Hiral, Attimarad, Mahesh, Mahesh Attimarad, Jigar Shah, Shery Jacob, Venugopala, Katharigatta N., Katharigatta N. Venugopala, Pottathil Shinu, Mewada, Vivek, Shah, Jigar, Shinu, Pottathil, Aldhubiab, Bandar, Sunita Chaudhary   +21 more
core   +1 more source

Nanoemulsion-based nasal in situ gel of olanzapine.

Journal of Excipients and Food Chemicals, 2023
Oral delivery of olanzapine suffers from low oral bioavailability and there has been reports of metabolic side effects. This study aimed to prepare a nanoemulsion of olanzapine and incorporate it into an in situ gel for nasal delivery.
Zahraa H Ali, Myasar Alkotaji
doaj  

Preparation of NLCs-Based Topical Erythromycin Gel: In Vitro Characterization and Antibacterial Assessment

Gels, 2022
In the present study, erythromycin (EM)-loaded nanostructured lipid carriers (NLCs) were prepared by the emulsification and ultra-sonication method. EM-NLCs were optimized by central composite design using the lipid (A), pluronic F127 (B) and sonication ...
Ameeduzzafar Zafar, Syed Sarim Imam, Mohd Yasir, Nabil K. Alruwaili, Omar Awad Alsaidan, Musarrat Husain Warsi, Shehla Nasar Mir Najib Ullah, Sultan Alshehri, Mohammed M. Ghoneim   +8 more
doaj   +1 more source

Archeologisch proefonderzoek (IVO-P) Burgermeester van Suchtelenstraat, Gemeente Beuningen

, 2021
Op 19 februari 2019 heeft Ex-Situ Archeologie een proefsleuvenonderzoek uitgevoerd op het perceel Burgermeester van Suchtelenstraat in de gemeente Beuningen.
Hoegen, drs R.D. (Ex-Situ Archeologie B.V.)
core   +1 more source

A Novel Numerical Model of Gelant Inaccessible Pore Volume for In Situ Gel Treatment [PDF]

, 2022
Inaccessible pore volume (IAPV) can have an important impact on the placement of gelant during in situ gel treatment for conformance control. Previously, IAPV was considered to be a constant factor in simulators, yet it lacked dynamic characterization ...
Bai, Baojun, Jianqiao Leng, Wei, Mingzhen, Xindi Sun, Mingzhen Wei, Baojun Bai, Leng, Jianqiao, Sun, Xindi   +7 more
core   +1 more source

Temperature-dependent in Situ Gel of Clotrimazole: an Experimental Study

Folia Medica, 2019
Background: The in-situ gel-forming polymeric formulations offer sustained and prolonged action in comparison to conventional drug delivery systems.
Patel Vipul P., Damasiya Harshad M., Kapupara Pankaj, Ashara Kalpesh C.   +3 more
doaj   +1 more source

APPLICATION AND CHARACTERIZATION OF IN SITU GEL

International Journal of Applied Pharmaceutics, 2018
Applications of in situ gel have been used for a variety of drug delivery routes, such as oral, ocular, rectal, vaginal and injection. Characterization of in situ gel was determined to ensure that the prepared preparation met the standard and it safe.
Insan Sunan Kurniawansyah, Iyan Sopyan, Nasrul Wathoni, Dasty Latifa Fillah, Rahadianti Umi Praditya   +4 more
openaire   +2 more sources

Controlled ocular drug delivery of ofloxacin using temperature modulated in situ gelling system

Journal of the Scientific Society, 2013
Background: The designing of ocular dosage form off ers complicated issues. Numerous protective mechanisms are present in the eye to prevent the absorption of drug candidate from the corneal membrane.
Upendra Nagaich, Nidhi Jain, Divya Kumar, Neha Gulati   +3 more
doaj   +1 more source

Ion-Triggered In Situ Gelling Intranasal Spray of Dronedarone Hydrochloride Nanocarriers: In Vitro Optimization and In Vivo Pharmacokinetic Appraisal

Pharmaceutics, 2022
The current study aims to develop niosomal nanocarriers for intranasal delivery of dronedarone hydrochloride to ameliorate its limited bioavailability. Niosomes were prepared by ethanol injection method and optimized using 3² full factorial experimental ...
Mahmoud H. Teaima, Doaa A. Helal, Jihad M. Alsofany, Mohamed A. El-Nabarawi, Mohamed Yasser   +4 more
doaj   +1 more source