Results 31 to 40 of about 193,900 (263)

Ion-Triggered In Situ Gelling Intranasal Spray of Dronedarone Hydrochloride Nanocarriers: In Vitro Optimization and In Vivo Pharmacokinetic Appraisal

open access: yesPharmaceutics, 2022
The current study aims to develop niosomal nanocarriers for intranasal delivery of dronedarone hydrochloride to ameliorate its limited bioavailability. Niosomes were prepared by ethanol injection method and optimized using 3² full factorial experimental ...
Mahmoud H. Teaima   +4 more
doaj   +1 more source

Unraveling the role of chitosan for nasal drug delivery systems: A review

open access: yesCarbohydrate Polymer Technologies and Applications, 2023
The discipline of nanoscience has made enormous strides in the recent two decades. The researchers in the field of nanomedicine have been looking into using natural biodegradable polymeric nano-colloids for targeted drug delivery, due to their high ...
Gurjeet Kaur   +6 more
doaj   +1 more source

Development and characterisation of thermo reversible mucoadhesive moxifloxacin hydrochloride in situ ophthalmic gel

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
A sustain release thermo reversible in situ gel of Moxifloxacin Hydrochloride using mucoadhesive polymer was prepared. Mucoadhesive polymer was used to obtain an ophthalmic delivery system with improved mechanical and mucoadhesive properties that will ...
M Dholakia, V Thakkar, N Patel, T Gandhi
doaj   +1 more source

Thermosensitive Pluronic® F127-Based in situ gel formulation containing nanoparticles for the sustained delivery of paclitaxel

open access: yesMedicine Science, 2023
Bone metastasis is one of the most encountered complications among cancer patients and majority of cancer types has led to bone metastasis. Paclitaxel (PCX) is an anticancer agent commonly used in cancer treatment. However, its clinical use is restricted
Sedat Unal   +3 more
doaj   +1 more source

APPLICATION AND CHARACTERIZATION OF IN SITU GEL

open access: yesInternational Journal of Applied Pharmaceutics, 2018
Applications of in situ gel have been used for a variety of drug delivery routes, such as oral, ocular, rectal, vaginal and injection. Characterization of in situ gel was determined to ensure that the prepared preparation met the standard and it safe.
Insan Sunan Kurniawansyah   +4 more
openaire   +2 more sources

In Vitro Evaluation of In Situ Gel

open access: yes, 2023
In Vitro Evaluation of In Situ Gel of the prepared formulas including: -Drug content -Osmolarity -Mucoadhesive force -Spreadability -Release ...
openaire   +1 more source

Review : In Situ Gel Optalmik

open access: yesFarmasetika.com (Online), 2019
In situ gel optalmik merupakan sediaan gel untuk mata yang awalnya berupa larutan, namun ketika diteteskan pada mata akan berubah menjadi gel sehingga waktu kontak dengan mata akan lebih lama. Pembuatan in situ gel menggunakan matriks-matriks yang mengental apabila berada pada kondisi fisiologi tertentu seperti pH, suhu dan konsentrasi ion.
Lutfiah Yusuf, Iyan Sopyan
openaire   +2 more sources

Characterization of beta-lactamases in situ on polyacrylamide gels [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1986
An inhibitor-based characterization system which allowed the identification of beta-lactamases after isoelectric focusing on polyacrylamide gels was developed. This system, using potassium clavulanate and oxacillin, distinguished type I chromosomally mediated enzymes from other beta-lactamases of gram-negative bacteria.
C C, Sanders, W E, Sanders, E S, Moland
openaire   +2 more sources

A mucoadhesive in situ gel delivery system for paclitaxel [PDF]

open access: yesAAPS PharmSciTech, 2006
MUC1 gene encodes a transmembrane mucin glycoprotein that is overexpressed in human breast cancer and colon cancer. The objective of this study was to develop an in situ gel delivery system containing paclitaxel (PTX) and mucoadhesives for sustained and targeted delivery of anticancer drugs.
Saurabh, Jauhari, Alekha K, Dash
openaire   +2 more sources

Development of an in-situ gel from CO2-captured complex solution and inhibiting coal spontaneous combustion: A case study in thermal engineering

open access: yesCase Studies in Thermal Engineering, 2023
The safety of underground coal mining is threatened by coal spontaneous combustion, making it essential to develop effective inhibitors to prevent such incidents.
Hemeng Zhang   +7 more
doaj   +1 more source

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