Results 51 to 60 of about 772,208 (306)

Understanding the deformation mechanism of individual phases of a ZrTi-based bulk metallic glass matrix composite using in situ diffraction and imaging methods [PDF]

, 2014
The plasticity of a ZrTi-based bulk metallic glass composite consisting of glassy matrix and crystalline dendritic phase was studied in-situ under identical tensile loading conditions using scanning electron microscopy and synchrotron X-ray diffraction ...
Connolley, Thomas, Huang, Yongjiang, Khong, J. C., Mi, J.   +3 more
core   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Annealing of defects in Fe after MeV Heavy ion irradiation

, 1998
We report study of recovery dynamics, followed by in-situ resistivity measurement after 100 MeV oxygen ion irradiation, in cold rolled Fe at 300K. Scaling behavior with microstructural density and temperature of sample have been used to establish stress ...
Cotterill R. M. J., Damask A. C., Dammak H. ., G Aggarwal, P Sen, Selishchev P. A., Silcox J.   +6 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Characteristics of in-situ stresses and engineering stability analysis on the south section of the Bohai Strait Cross-Sea Corridor project

Dizhi lixue xuebao
Objective  The Bohai Strait Cross-Sea Corridor is an important maritime traffic project which joins the Liaodong and the Shandong peninsulas. The state of geostress is an important reference for engineering design and construction decision-making ...
QIAO Erwei, MA Xiumin, GUO Hualin, Sun Yao, JIANG Jingjie   +4 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Determination of In-Situ Stress and Geomechanical Properties from Borehole Deformation

Energies, 2018
This paper proposes a cost-effective technique to determine geomechanical properties and in-situ stress from borehole deformation data. In this approach, an artificial neural network (ANN) is applied to map the relationship among in-situ stress, borehole
Hong Xue Han, Shunde Yin
doaj   +1 more source

In situ stress state in Mainland China [PDF]

pure and applied geophysics, 1995
In situ stress measurements are one of the important methods for studying the recent tectonic stress field and stress state. In this paper, the stress state and variation of stresses with depth in Mainland China are presented and analyzed on the basis of in situ stress data measured by both hydrofracturing and overcoring techniques.
openaire   +1 more source

Real-time Measurement of Stress and Damage Evolution During Initial Lithiation of Crystalline Silicon

, 2011
Crystalline to amorphous phase transformation during initial lithiation in (100) silicon-wafers is studied in an electrochemical cell with lithium metal as the counter and reference electrode.
A. McCormick, A. R. Kamali, M. J. Chon, P. R. Guduru, S. Komaba, V. A. Sethuraman, V. Srinivasan   +6 more
core   +1 more source