Results 51 to 60 of about 620,275 (284)

Surfactant-free gelatin-stabilised biodegradable polymerised high internal phase emulsions with macroporous structures

Frontiers in Chemistry, 2023
High internal phase emulsion (HIPE) templating is a well-established method for the generation of polymeric materials with high porosity (>74%) and degree of interconnectivity.
Rachel Furmidge, Rachel Furmidge, Caitlin E. Jackson, Caitlin E. Jackson, María Fernanda Velázquez de la Paz, María Fernanda Velázquez de la Paz, Victoria L. Workman, Victoria L. Workman, Nicola H. Green, Nicola H. Green, Gwendolen C. Reilly, Gwendolen C. Reilly, Vanessa Hearnden, Vanessa Hearnden, Frederik Claeyssens, Frederik Claeyssens   +15 more
doaj   +1 more source

Uji In Silico Senyawa Emodin sebagai Ligan pada Reseptor Estrogen Alfa [PDF]

, 2015
Breast cancer is a disease with abnormal cell proliferation at breast tissue that can invade the surrounding tissue and spread to another organ. Based on WHO (2014) at 2012, there are 48,998 breast cancer cases on women in Indonesia with 19,730 death ...
Istyastono, E. P. (Enade), Liliana, L. (Liliana)   +1 more
core  

Agent-based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity. [PDF]

, 2013
A crisis continues to brew within the pharmaceutical research and development (R&D) enterprise: productivity continues declining as costs rise, despite ongoing, often dramatic scientific and technical advances. To reverse this trend, we offer various
Hunt, C. Anthony, Hunt, CA, Kennedy, RC, Kim, SHJ, Ropella, GEP   +4 more
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Associations between Physical Exercise, Quality of Life, Psychological Symptoms and Treatment Side Effects in Early Breast Cancer

The Breast Journal, 2022
Background. Identifying and understanding modifiable factors for the well-being of cancer patients is critical in survivorship research. We studied variables associated with the exercise habits of breast cancer patients and investigated if the ...
Leena Vehmanen, Johanna Mattson, Evangelos Karademas, Albino J. Oliveira-Maia, Berta Sousa, Ruth Pat-Horenczyk, Ketti Mazzocco, Panagiotis Simos, Fátima Cardoso, Greta Pettini, Chiara Marzorati, Eleni Kolokotroni, Georgios Stamatakos, Diana Frasquilho, Paula Poikonen-Saksela   +14 more
doaj   +1 more source

Therapeutic target discovery using Boolean network attractors: avoiding pathological phenotypes [PDF]

, 2014
Target identification, one of the steps of drug discovery, aims at identifying biomolecules whose function should be therapeutically altered in order to cure the considered pathology.
Boissel, Jean-Pierre, Poret, Arnaud
core   +4 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Whole genome sequence of petroleum hydrocarbon degrading novel strain Microbacter sp. EMBS2025 isolated from Chilika Lake, Odisha, India

Scientific Reports
Bioremediation offers a sustainable and eco-friendly approach for addressing petroleum contamination. In this study, we investigated the hydrocarbon-degrading potential of Microbacter sp.
Anuraj Nayarisseri, Khushboo Sharma, Arshiya Khan, Radhika Swami, Rinku Chaudhary, Juhi Sharma, Navpreet Kaur, Jyotsana Kharate, Vasudha Rathore, Leena Prajapati, Srinivas Bandaru, Francisco Jaime Bezerra Mendonça Junior, Marcus T. Scotti, Luciana Scotti   +13 more
doaj   +1 more source

Author Correction: Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail

Scientific Reports, 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Marwa M. Mahmoud, Jovana Serbanovic-Canic, Shuang Feng, Celine Souilhol, Rouyu Xing, Sarah Hsiao, Akiko Mammoto, Jing Chen, Markus Ariaans, Sheila E. Francis, Kim Van der Heiden, Victoria Ridger, Paul C. Evans   +12 more
doaj   +1 more source

In Silico Studies on DARC

Infectious Disorders - Drug Targets, 2009
The Duffy Antigen/Receptor for Chemokine (DARC) is a seven segment transmembrane protein. It was firstly discovered as a blood group antigen and was the first specific gene locus assigned to a specific autosome in man. It became more famous as an erythrocyte receptor for malaria parasites (Plasmodium vivax and Plasmodium knowlesi), and finally for ...
de Brevern, Alexandre, Autin, Ludovic, Colin, Yves, Bertrand, Olivier, Etchebest, Catherine   +4 more
openaire   +4 more sources