Results 31 to 40 of about 423,064 (316)
In silico experimental modeling of cancer treatment [PDF]
, 2012 In silico experimental modeling of cancer involves combining findings from biological literature with computer-based models of biological systems in order to conduct investigations of hypotheses entirely in the computer laboratory.
Trisilowati, Mallet, Daniel G.
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Global reactivity models are impactful in industrial synthesis applications
Journal of Cheminformatics, 2023 Artificial Intelligence is revolutionizing many aspects of the pharmaceutical industry. Deep learning models are now routinely applied to guide drug discovery projects leading to faster and improved findings, but there are still many tasks with enormous ...
Paulo Neves +8 more
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Toward in silico Catalyst Optimization
, 2022 In this minireview, we overview a computational pipeline that can be used to successfully reproduce the enantiomeric ratios of homogeneous catalytic reactions.
Nicolai, Cramer +4 more
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Carbonyl trapped in silico [PDF]
Nature Reviews Chemistry, 2020 A persistent silylene complex of CO is reminiscent of metal carbonyls and features interesting bonding interactions.
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The microcircuits of striatum in silico [PDF]
Proceedings of the National Academy of Sciences, 2020 The basal ganglia play an important role in decision making and selection of action primarily based on input from cortex, thalamus, and the dopamine system. Their main input structure, striatum, is central to this process. It consists of two types of projection neurons, together representing 95% of the neurons, and 5% of interneurons, among which are ...
Hjorth, J. J. Johannes +11 more
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In Silico Protein Motif Discovery and Structural Analysis
, 2021 A wealth of in silico tools is available for protein motif discovery and structural analysis. The aim of this chapter is to collect some of the most common and useful tools and to guide the biologist in their use.
Davey, Norman E. +5 more
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Cancer Informatics, 2015 Intensive glioma tumor infiltration into the surrounding normal brain tissues is one of the most critical causes of glioma treatment failure. To quantitatively understand and mathematically simulate this phenomenon, several diffusion-based mathematical ...
Markos Antonopoulos, Georgios Stamatakos
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Combined In Silico, In Vivo, and In Vitro Studies Shed Insights into the Acute Inflammatory Response in Middle-Aged Mice [PDF]
, 2013 We combined in silico, in vivo, and in vitro studies to gain insights into age-dependent changes in acute inflammation in response to bacterial endotoxin (LPS). Time-course cytokine, chemokine, and NO2-/NO3- data from "middle-aged" (6-8 months old) C57BL/
Vodovotz, Yoram +36 more
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Applied Sciences, 2022 Finite element (FE) analyses contribute to a better understanding of the human lumbar spine’s biomechanics and serve as an effective predictive tool.
Mate Turbucz +6 more
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, 2020 Fatty acid esters of hydroxy fatty acids (FAHFAs) are a family of recently discovered lipids with important physiological functions in mammals and plants.
Yu-Qi Feng +13 more
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