Results 221 to 230 of about 497,128 (308)

"In silico analysis of human TLR3 missense single nucleotide polymorphisms and their potential association with cancer". [PDF]

Sci Rep
Agarwal M, Kumar M, Dahiya S, Kumar A, Tripathi R, Bala K.   +5 more
europepmc   +1 more source

Decoding Tattoo and Permanent Makeup Pigments: Linking Physicochemical Properties to Absorption, Distribution, Metabolism, and Elimination Profiles Using Quantitative Structure–Activity Relationship (QSAR)‐Based New Approach Methodologies (NAMs)

Advanced Intelligent Discovery, EarlyView.
This study applies QSAR‐based new approach methodologies to 90 synthetic tattoo and permanent makeup pigments, revealing systemic links between their physicochemical properties and absorption, distribution, metabolism, and elimination profiles. The correlation‐driven analysis using SwissADME, ChemBCPP, and principal component analysis uncovers insights
Girija Bansod, Ajay Vikram Singh, Preeti Bhardwaj, Tulika Rai, Sweta Vijay Nakhale, Amruta Shelar, Rajendra Patil, Peter Laux, Andreas Luch, Christopher J. Osgood, Michael W. Stacey   +10 more
wiley   +1 more source

Phenotype-Driven Next-Generation Sequencing and Structure-Based In Silico Analysis Reveal Disease-Specific Diagnostic Yield and Genotype-Phenotype Correlations in Inherited Kidney Diseases. [PDF]

Life (Basel)
Baris S, Terali K, Bozlak S, Yilmaz N, Yilmaz HI, Yavas C, Eroz R, Hazaloglu M, Ozen K, Gezdirici A, Dogan M, Kilic H, Demir S, Baris I.   +13 more
europepmc   +1 more source

Advanced Experiment Design Strategies for Drug Development

Advanced Intelligent Discovery, EarlyView.
Wang et al. analyze 592 drug development studies published between 2020 and 2024 that applied design of experiments methodologies. The review surveys both classical and emerging approaches—including Bayesian optimization and active learning—and identifies a critical gap between advanced experimental strategies and their practical adoption in ...
Fanjin Wang, Anthony Harker, Mohan Edirisinghe, Maryam Parhizkar   +3 more
wiley   +1 more source

SOPs for in-silico analysis of TAVI

Providing standard protocols for performing CFD and FSI simulation as well as PIV measurements of TAVI in medical device ...
openaire   +1 more source

A Generalized Framework for Data‐Efficient and Extrapolative Materials Discovery for Gas Separation

Advanced Intelligent Discovery, EarlyView.
This study introduces an iterative supervised machine learning framework for metal‐organic framework (MOF) discovery. The approach identifies over 97% of the best performing candidates while using less than 10% of available data. It generalizes across diverse MOF databases and gas separation scenarios.
Varad Daoo, Jayant K. Singh
wiley   +1 more source

In silico Analysis of Combinatorial microRNA Activity Reveals Target Genes and Pathways Associated with Breast Cancer Metastasis

Cancer Informatics, 2011
Alan A. Dombkowski, Zakia Sultana, Douglas B. Craig, Hasan Jamil   +3 more
doaj  

In silico analysis of fixation device strain patterns in the postoperative proximal femur: Effects of bone quality during gait. [PDF]

Clin Biomech (Bristol)
Kumaran Y, Soehnlen S, Haritos C, Jhaveri S, Tripathi S, Shaikh H, Di Stasi S, Quatman CE.   +7 more
europepmc   +1 more source

A Computational Approach for Biomimetic Design of Liver‐On‐A‐Chip

Advanced Intelligent Discovery, EarlyView.
A biomimetic liver‐on‐a‐chip with antiparallel perfusion was designed using COMSOL‐guided simulation to replicate hepatic acinus transport. Full‐scale modelling revealed diffusion‐dominated, length‐dependent nutrient gradients and low‐shear conditions.
Zhenxu Yang, Qiankun Yin, Qingxin Liu, Zhejun Xu, Ye Zhang, Christopher Vega‐Sánchez, Xiaochen Liu, Daniele Vigolo, Jiao Jiao Li, Ken‐Tye Yong   +9 more
wiley   +1 more source

Discovery of Tyrosinase Inhibitors from <i>Lysinibacillus</i> sp. JNUCC 52 via Genome Mining, Secondary Metabolites Profiling, and In Silico Analysis. [PDF]

Curr Issues Mol Biol
Liang X, Xu Y, Hyun CG.
europepmc   +1 more source