Results 11 to 20 of about 115,710,970 (297)

Smart Approach for the Design of Highly Selective Aptamer-Based Biosensors

open access: yesBiosensors, 2022
Aptamers are chemically synthesized single-stranded DNA or RNA oligonucleotides widely used nowadays in sensors and nanoscale devices as highly sensitive biorecognition elements. With proper design, aptamers are able to bind to a specific target molecule
Ali Douaki   +8 more
doaj   +1 more source

Evaluation of personalized right ventricle to pulmonary artery conduits using in silico design and computational analysis of flowCentral MessagePerspective

open access: yesJTCVS Open, 2020
Objectives: Right ventricle to pulmonary artery (RV-PA) conduits are required for the surgical management of pulmonary atresia with ventricular septal defect and truncus arteriosus.
Pegah Ebrahimi, MPhil   +6 more
doaj   +1 more source

Alignment independent 3D-QSAR, quantum calculations and molecular docking of Mer specific tyrosine kinase inhibitors as anticancer drugs

open access: yesSaudi Pharmaceutical Journal, 2016
Mer receptor tyrosine kinase is a promising novel cancer therapeutic target in many human cancers, because abnormal activation of Mer has been implicated in survival signaling and chemoresistance.
Fereshteh Shiri   +2 more
doaj   +1 more source

Gendered Design in STEAM Bulletin: Issue Two, March 2021

open access: yes, 2022
Gendered Design in STEAM (science, technology, engineering, art and mathematics) for Lower-and-Middle-Income-Countries (LMICs) is a three year program (2019-2022) funded by the International Development Research Centre and facilitated by Carleton ...
Gendered Design in STEAM
core   +2 more sources

Modification of Vegetable Proteins to Release Bioactive Peptides Able to Treat Metabolic Syndrome—In Silico Assessment

open access: yesApplied Sciences, 2020
Metabolic syndrome comprises a cluster of diseases like hypertension, dyslipidemia, and insulin resistance, among others. Its treatment is based on lifestyle modification; however, this treatment often fails to improve metabolic syndrome indicators over ...
Diego Armando Maldonado-Torres   +4 more
doaj   +1 more source

Gendered Design in STEAM Bulletin: Issue Three, May 2021

open access: yes, 2023
Gendered Design in STEAM (science, technology, engineering, art and mathematics) for Lower-and-Middle-Income-Countries (LMICs) is a three year program (2019-2022) funded by the International Development Research Centre and facilitated by Carleton ...
Gendered Design in STEAM
core   +2 more sources

In Silico-Based Design of a Hybrid Peptide with Antimicrobial Activity against Multidrug-Resistant Pseudomonas aeruginosa Using a Spider Toxin Peptide

open access: yesToxins, 2023
The escalating prevalence of antibiotic-resistant bacteria poses an immediate and grave threat to public health. Antimicrobial peptides (AMPs) have gained significant attention as a promising alternative to conventional antibiotics.
Min Kyoung Shin   +8 more
doaj   +1 more source

Gendered Design in STEAM Bulletin : Issue One, January 2021

open access: yes, 2022
Gendered Design in STEAM (science, technology, engineering, art and mathematics) for Lower-and-Middle-Income-Countries (LMICs) is a three year program (2019-2022) funded by the International Development Research Centre and facilitated by Carleton ...
Gendered Design in STEAM
core   +2 more sources

Gendered Design in STEAM Bulletin: Issue Four, July 2021

open access: yes, 2023
Gendered Design in STEAM (science, technology, engineering, art and mathematics) for Lower-and-Middle-Income-Countries (LMICs) is a three year program (2019-2022) funded by the International Development Research Centre and facilitated by Carleton ...
Gendered Design in STEAM
core   +2 more sources

In silico design of anti-atherogenic biomaterials [PDF]

open access: yesBiomaterials, 2013
Atherogenesis, the uncontrolled deposition of modified lipoproteins in inflamed arteries, serves as a focal trigger of cardiovascular disease (CVD). Polymeric biomaterials have been envisioned to counteract atherogenesis based on their ability to repress scavenger mediated uptake of oxidized lipoprotein (oxLDL) in macrophages.
Lewis, Daniel R   +7 more
openaire   +4 more sources

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