Results 31 to 40 of about 119,597,839 (255)

In silico Design, and In vitro Expression of a Fusion Protein Encoding Brucella abortus L7/L12 and SOmp2b Antigens

Advanced Biomedical Research, 2018
Background: L7/L12 is a protective antigen conserved in main Brucella pathogens and is considered as potential vaccine candidate. Outer membrane protein 2b is an immunogen conserved in all Brucella pathogens.
Maryam Golshani, Melina Ghasemian, Nematollah Gheibi, Saeid Bouzari   +3 more
doaj   +1 more source

Evaluating the use of a novel low-cost measurement insole to characterise plantar foot strain during gait loading regimes

Frontiers in Bioengineering and Biotechnology, 2023
Introduction: Under plantar loading regimes, it is accepted that both pressure and shear strain biomechanically contribute to formation and deterioration of diabetic foot ulceration (DFU).
Sarah R. Crossland, Heidi J. Siddle, Claire L. Brockett, Peter Culmer   +3 more
doaj   +1 more source

Gendered Design in STEAM Bulletin : Issue One, January 2021

, 2022
Gendered Design in STEAM (science, technology, engineering, art and mathematics) for Lower-and-Middle-Income-Countries (LMICs) is a three year program (2019-2022) funded by the International Development Research Centre and facilitated by Carleton ...
Gendered Design in STEAM
core   +2 more sources

Toward in silico Catalyst Optimization [PDF]

, 2022
In this minireview, we overview a computational pipeline that can be used to successfully reproduce the enantiomeric ratios of homogeneous catalytic reactions.
Nicolai, Cramer, Ruben, Laplaza, Markus, Reiher, Clemence, Corminboeuf, Matthew, Wodrich, Markus Reiher, Matthew Wodrich, Ruben Laplaza, Nicolai Cramer, Clemence Corminboeuf   +9 more
core   +1 more source

Gendered Design in STEAM Bulletin: Issue Five, November 2021

, 2023
Gendered Design in STEAM (science, technology, engineering, art and mathematics) for Lower-and-Middle-Income-Countries (LMICs) is a three year program (2019-2022) funded by the International Development Research Centre and facilitated by Carleton ...
Gendered Design in STEAM
core   +2 more sources

Virtual screening of phytochemical compounds as potential inhibitors against SARS-CoV-2 infection

Beni-Suef University Journal of Basic and Applied Sciences, 2021
Background The present pandemic situation due to coronavirus has led to the search for newer prevention, diagnostic, and treatment methods. The onset of the corona infection in a human results in acute respiratory illness followed by death if not ...
Ram Kothandan, Cashlin Anna Suveetha Gnana Rajan, Janamitra Arjun, Rejoe Raymond Michael Raj, Sowfia Syed   +4 more
doaj   +1 more source

DNA module platform for developing colorimetric aptamer sensors

BioTechniques, 2016
Here we present a DNA module platform for developing simple aptamer sensors based on a microarray format combined with secondary structure prediction in silico.
Yasuyuki Tomita, Yuji Morita, Hiroaki Suga, Daisuke Fujiwara   +3 more
doaj   +1 more source

Interpretable machine learning classifies β-lactamase subclasses and prioritizes boundary variants for antimicrobial resistance surveillance

Frontiers in Pharmacology
IntroductionAntimicrobial resistance is a major global health threat, and β-lactamase-mediated inactivation of β-lactam antibiotics remains a leading cause of treatment failure.
Rahul Kaushik, Suyong Re
doaj   +1 more source

In-silico Design of Multi-epitope Vaccine against Nipah Virus using Immunoinformatics Approach

Journal of Pure and Applied Microbiology, 2021
Nipah virus is a pleomorphic virus that causes high mortality with unpredictable outbreaks. The virus also shows high zoonotic potential with long term neurological damage after recovery further adding to the disease burden.
Suraj Raju, Debasish Sahoo, Vikas Kumar Bhari   +2 more
doaj   +1 more source

Artificial intelligence directed computational protein design: lessons from COVID-19 for pandemic-ready vaccines and antibody therapeutics

Journal of Pharmacy & Pharmaceutical Sciences
Artificial intelligence (AI) directed computational protein design has emerged as a transformative force in modern therapeutic discovery, reshaping how vaccines and antibody-based interventions are conceived, optimized, and deployed against emerging ...
Rahul Kaushik, Suyong Re
doaj   +1 more source