Results 111 to 120 of about 114,431,160 (255)

Advancing the 3Rs in bone tissue engineering: emerging in vitro, in silico, and refined in vivo strategies

Frontiers in Physiology
Tissue engineering is an interdisciplinary field integrating materials science, biology, chemistry, and immunology to develop regenerative solutions for complex tissues. Validation of tissue-engineered therapies, however, remains challenging—particularly
Adelaide L. Cagle, Afton K. Limberg, Amritha Anup, Aleyna E. La Croix, Katherine R. Hixon, Katherine R. Hixon   +5 more
doaj   +1 more source

amostof/In-silico-model-development-paper: v1.0

<p>The code for the paper "In silico model development and optimization of in vitro lung cell population growth" submitted to PLOS One</p ...
Amirmahdi Mostofinejad
core   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

Advanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh, Peyman GhavamiNejad, Arash Khorrami Jahromi, Sanjana Srikant, Sripadh Guptha Yedire, Fatemeh Keyvani, Roozbeh Siavash Moakhar, Sajad Shiekh, Mackenzie Graham, Joe Quadrilatero, Mahla Poudineh, Sara Mahshid   +11 more
wiley   +1 more source

International Conference for Mathematical Modeling and Optimization in Mechanics, 6-7 March, 2014, Jyväskylä, Finland : honor of the 70th anniversary of Prof. Nikolay Banichuk

, 2014
This book of abstracts presents materials of the International Conference for Mathematical Modeling and Optimization in Mechanics (MMOM 2014) 6-7 March 2014, Jyväskylä, Finland.
International Conference for Mathematical Modeling and Optimization in Mechanics
core   +1 more source

Considering Population Variability of Electrophysiological Models Improves the In Silico Assessment of Drug-Induced Torsadogenic Risk

, 2022
This repository contains the parameter sets of the population of TorORd models and the the population of ORdmD models, the ORdmD CellML file and MALTAB code used in Llopis-Lorente, J., Trenor, B., Saiz, J. (2022).
Trenor Gomis, Beatriz Ana, Saiz Rodríguez, Francisco Javier, Llopis Lorente, Jordi   +2 more
core  

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

Large‐Scale Determination of Frontier Orbital Energies of Disordered Small‐Molecule Organic Semiconductors Using Exciplex Emission Spectra

Advanced Materials, EarlyView.
ABSTRACT Accurately knowing the frontier orbital energies of the structurally disordered small‐molecule organic semiconductors that are used in optoelectronic devices such as organic light‐emitting diodes is required to rationally improve their performance. Here, we show that these energies can be deduced with a large accuracy from the peak energies of
Christian B. McDonald, Hiroki Tomita, Giacomo Cotelli, Louka L. Brüll, Nanno G. de Rooij, Lucas R.L. Norg, Milo Clément, Reinder Coehoorn   +7 more
wiley   +1 more source

Deciphering nifedipine in vivo delivery from modified release dosage forms: Identification of food effect

Acta Pharmaceutica, 2015
With the increased reliance on in vitro dissolution testing as an indicator of in vivo drug behavior and the trend towards the in silico modeling of dosage form performance, the need for bioperformance dissolution methodology development has been ...
Ilić Marija, Kovačević Ivan, Parojčić Jelena   +2 more
doaj   +1 more source

There's more to a model than code: understanding and formalizing in silico modeling experience

, 2005
Mapping biology into computation has both a domain specific aspect -- biological theory -- and a methodological aspect -- model development. Computational modelers have implicit knowledge that guides modeling in many ways but this knowledge is rarely ...
Geard, N L, Willadsen, K, Mattick, J, Wiles, J, Hallinan, J, Watson, J, Bradley, D   +6 more
core   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

Advanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz, Matthieu Gelin, Lucas Pradeau‐Phélut, Arrate Muñoz‐Barrutia, Sandrine Etienne‐Manneville, Daniel Garcia‐Gonzalez   +5 more
wiley   +1 more source