Results 101 to 110 of about 84,932 (303)

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Computing Opportunity Costs of Growing Local Varieties for On-farm Conservation: Illustrations Using Sorghum Data from Ethiopia [PDF]

The recent shift of emphasis to on-farm conservation is driven by its diverse attractive features - participatory nature, dynamic nature, capacity to maintain not only crop diversity but the knowledge that evolves with it, the chance it offers and the ...
Mburu, John G., Estrella, Jaime, Wale, Edilegnaw   +2 more
core   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Uprooting Diversity? Peasant Farmers’ Market Engagements and the on-Farm Conservation of Crop Genetic Resources in the Guatemalan Highlands [PDF]

The long-term security of the global food supply is contingent upon the on-farm conservation of crop genetic diversity. Without it, food crops lack the ability to evolve in the face of new pests, emerging plant diseases, and changing environmental ...
S. Ryan Isakson
core  

R Code and Output Supporting: Breeding behaviors of an endangered prairie butterfly in relation to environmental factors in an ex situ conservation setting [PDF]

Please see the attached readme file for details regarding the data. Code file was updated on 2026-01-23 to reflect reviewer feedback.This repository contains the data, supplementary material, and R code and associated output supporting the results ...
Fieberg, John, Stapleton, Seth, Thomas, Amaya, Runquist, Erik, Nordmeyer, Cale   +4 more
core   +2 more sources

Le patrimoine des Soieries Bonnet (Jujurieux, Ain) : conserver et valoriser in situ un ensemble unique de l’industrie textile [PDF]

, 2016
Le site et les collections des Soieries Bonnet à Jujurieux (Ain) constituent un ensemble exceptionnel, significatif de l’histoire de Lyon et de sa région aux XIXe et XXe siècles. À la cessation d’activité de l’entreprise fin 2001, les biens de la société
Nathalie Foron-Dauphin, sous la direction de Delphine Cano, Foron-Dauphin, Nathalie, Cano, sous la direction de Delphine   +3 more
core   +1 more source

Biobanking in forestry practices: towards an agency policy?

New Genetics and Society, 2018
The conservation-management of living beings is not only an issue in medicine. Based on a collaboration between a sociologist and a geneticist, this paper aims to document the banking practices in the sector of forest genetic resources, which raises ...
Fabien Milanovic, François Lefèvre
doaj   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

Advanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu, Ke Cao, Liping Guan, Aizhi Qin, Yong Li, Zihao Zhao, Yinpeng Zhang, Yaping Zhou, Lirong Wang, Xuwu Sun   +9 more
wiley   +1 more source

VARIETY CHARACTERISTICS AND THE LAND ALLOCATION DECISIONS OF FARMERS IN A CENTER OF MAIZE DIVERSITY [PDF]

There is emerging interest in the prospects for enhancing farmers' management of genetic resources as a complementary strategy to ex situ conservation.
Aguirre, Alfonso, Smale, Melinda, Bellon, Mauricio R.   +2 more
core   +1 more source

PGRFA Management of Outcrossing Plants Propagated by Seed: From On-Farm to Ex Situ Conservation and Some Italian Maize Case Studies

Agronomy
In this review, the main issues related to the conservation and valorization of Plant Genetic Resources for Food and Agriculture (PGRFA) will be primarily addressed.
Michela Landoni, Anna Bertoncini, Martina Ghidoli, Graziano Rossi, Elena Cassani, Sabrina Locatelli, Carlotta Balconi, Roberto Pilu   +7 more
doaj   +1 more source