Results 61 to 70 of about 231,900 (200)

Fluorescent labeling of plasmid DNA and mRNA : gains and losses of current labeling strategies [PDF]

, 2016
Live-cell imaging has provided the life sciences with insights into the cell biology and dynamics. Fluorescent labeling of target molecules proves to be indispensable in this regard. In this Review, we focus on the current fluorescent labeling strategies
Rombouts, Koen, Braeckmans, Kevin, Remaut, Katrien   +2 more
core   +1 more source

Regulation of StAR by the N-terminal domain and co-induction of SIK1 and TIS11b/Znf36l1 in single cells.

Frontiers in Endocrinology, 2016
The cholesterol transfer function of StAR is uniquely integrated into adrenal cells, with mRNA translation and PKA phosphorylation occurring at the mitochondrial outer membrane (OMM).
Jinwoo Lee, Tiegang Tong, Yeehoon Foong, Ibrahim Musaitif, Takeshi Yamazaki, Colin Jefcoate   +5 more
doaj   +1 more source

Detection of t(7;12)(q36;p13) in paediatric leukaemia using dual colour fluorescence in situ hybridisation [PDF]

, 2015
The identification of chromosomal rearrangements is of utmost importance for the diagnosis and classification of specific leukaemia subtypes and therefore has an impact on therapy choices in individual cases.
Federico, C, Owoka, T, Saccone, S, Tosi, S, Vetter, M   +4 more
core   +2 more sources

High resolution physical mapping of single gene fragments on pachytene chromosome 4 and 7 of Rosa [PDF]

, 2015
Background: Rosaceae is a family containing many economically important fruit and ornamental species. Although fluorescence in situ hybridization (FISH)-based physical mapping of plant genomes is a valuable tool for map-based cloning, comparative ...
Khrustaleva, Ludmila I, Kirov, Ilya V, Van Laere, Katrijn   +2 more
core   +2 more sources

Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes [PDF]

, 1988
Chromosome aberrations in two glioma cell lines were analyzed using biotinylated DNA library probes that specifically decorate chromosomes 1, 4, 7, 18 and 22 from pter to qter.
A Al-Saadi, AG Knudson, B Trask, CD Bloomfield, D Pinkel, D. C. Ward, F Mitelman, G Rappold, GM Brodeur, GT Merlino, H Harris, H Yamazaki, HE McDermid, J Burns, J. Borden, JA Rey, JE Landegent, JR Shapiro, JS Waye, L Larizza, L Manuelidis, L Manuelidis, L Manuelidis, L. Manuelidis, LC Showe, M Schardin, MF Hansen, NB Atkin, P Lichter, P. Lichter, SH Bigner, SH Bigner, SH Bigner, T Boveri, T Cremer, T Cremer, T. Cremer, TA Libermann, W Henn   +38 more
core   +1 more source

Prevalence of cytogenetic and electrophoretic abnormalities in patients suspected of multiple myeloma [PDF]

Medical Laboratory Journal
Background: Multiple myeloma (MM) is a blood cancer characterized by the uncontrolled growth of plasma cells in the bone marrow. It typically develops from monoclonal gammopathy of undetermined significance (MGUS), which can progress to smoldering ...
Amudha Subramaniam, Saranya Raj, Thashreefa Olakara, Jaya Kumari S, Veronica Preetha Tilak   +4 more
doaj  

Protocol optimization improves the performance of multiplexed RNA imaging

Scientific Reports
Spatial transcriptomics has emerged as a powerful tool to define the cellular structure of diverse tissues. One such method is multiplexed error robust fluorescence in situ hybridization (MERFISH).
Josh J. Luce, Christian A. Reardon-Lochbaum, Paolo Cadinu, Rosalind J. Xu, Jose Aceves-Salvador, Evangelia Semizoglou, Bertrand Wong, Iris Lopez, Alan B. Cantor, William Renthal, Jeffrey R. Moffitt   +10 more
doaj   +1 more source

Molecular cytotaxonomy of primates by chromosomal in situ suppression hybridization [PDF]

, 1990
A new strategy for analyzing chromosomal evolution in primates is presented using chromosomal in situ suppression (CISS) hybridization. Biotin-labeled DNA libraries from flow-sorted human chromosomes are hybridized to chromosome preparations of ...
Anna Jauch, Bickmore, Cremer, Cremer, de Grouchy, Dutrillaux, Holmquist, Johannes Wienberg, Lalley, Lichter, Lichter, Lichter, O'Brien, Ohno, Pinkel, Roscoe Stanyon, Seuánez, Stanyon, Thomas Cremer, Van Dilla, Weber, Wienberg, Yunis   +22 more
core   +1 more source

Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis [PDF]

, 2020
Spontaneous intracellular calcium activity can be observed in a variety of cell types and is proposed to play critical roles in a variety of physiological processes.
Ablondi, Eileen F., Halleran, Andrew D., Kemper, Peter, Marken, John P., Paudel, Sudip, Rahman, Atiqur, Saha, Margaret S., Sehdev, Morgan   +7 more
core  

Cellular bases of the RNA metabolism dysfunction in motor neurons of a murine model of spinal muscular atrophy: Role of Cajal bodies and the nucleolus [PDF]

, 2017
Spinal muscular atrophy (SMA) is caused by a homozygous deletion or mutation in the survival motor neuron 1 (SMN1) gene that leads to reduced levels of SMN protein resulting in degeneration of motor neurons (MNs).
Berciano, Maria T., Calderó i Pardo, Jordi, Lafarga, Miguel, Narcís, Oriol J., Piedrafita Llorens, Lídia, Riancho, Javier, Tapia, Olga, Tarabal Mostazo, Olga   +7 more
core   +2 more sources