Results 171 to 180 of about 26,404 (336)

<i>In Situ</i> Hypothermic Perfusion in Hepatectomy for Advanced Hepatoblastoma: A Case Report and Literature Review. [PDF]

Surg Case Rep
Matsuura T, Yanagi Y, Kawakubo N, Kajihara K, Shirai T, Uchida Y, Toriigahara Y, Yoshizumi T, Tajiri T.   +8 more
europepmc   +1 more source

Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug‐resistant epilepsy: From operating room to wet lab

Epilepsia Open, EarlyView.
Abstract Objective We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...
Jenni Kyyriäinen, Adriana Della Pietra, Mastaneh Torkamani‐Azar, Mireia Gómez‐Budia, Polina Abushik, Nataliia Novosolova, Henri Eronen, Omar Narvaez, Ekaterina Paasonen, Vera Lezhneva, Anssi Pelkonen, Liudmila Saveleva, Antti Huotarinen, Ilya Belevich, Eija Jokitalo, Kuopio Epilepsy Center Epilepsy Surgery Group, Leena Jutila, Tuomas Rauramaa, Arto Immonen, Ville Leinonen, Jussi Tohka, Olli Gröhn, Reetta Kälviäinen, Tarja Malm, Alejandra Sierra   +24 more
wiley   +1 more source

Preparation of Lipid Cubic Liquid Crystalline Nanoparticles of Sinomenine Based on Molecular Dynamics Simulations and Investigation of the Efficacy Against Rheumatoid Arthritis. [PDF]

Int J Mol Sci
Zhu J, Li J, Zou Y, Ding X, Li J, Xu J, Xiao Y, Qiu Y, Xu W.   +8 more
europepmc   +1 more source

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

Interdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang, Jiaqi Zhou, Hang Qiao, Yifan Jia, Ling Ye, Zeli Li, Jiahe Ouyang, Haoxian Zhou, Kangxin Zeng, Xuemeng Wang, Yixian Wang, Yang Zhang, Yupeng Zhang, Yizhou Cai, Yutao Hu, Minzhe Zhang, Wenwei Xu, Zhenzhen Wu, Xiaofang Qiu, Li Lin   +19 more
wiley   +1 more source

Assessment of intestinal permeability of furosemide by means of in situ perfusion model in rats

, 2015
Juliana Pereira Maura Rossato, Marina de Freitas Silva, Cristina Helena dos Reis Serra   +2 more
openalex   +1 more source

An Iterative Design Approach to Development of an Ex Situ Normothermic Multivisceral Perfusion Platform. [PDF]

J Clin Med
van Leeuwen LL, Holzner ML, McKenney C, Todd R, Frost JK, Gudibendi S, Kim-Schluger L, Schiano T, Florman S, Akhtar MZ.   +9 more
europepmc   +1 more source

Adipose‐derived small extracellular vesicles exacerbate microvascular dysfunction in heart failure with preserved ejection fraction via mmu‐miR‐582‐3p‐mediated Rap1b suppression

Interdisciplinary Medicine, EarlyView.
This study reveals that small extracellular vesicles (sEVs) from visceral fat compromise coronary microcirculation in a mouse model of heart failure with preserved ejection fraction (HFpEF). The SGLT2 inhibitor canagliflozin emerges as a therapeutic strategy, improving cardiac function and endothelial health.
Lu Chen, Qiuhan Wang, Mengjia Shen, Mingjue Li, Yingqi Zhu, Cankun Zheng, Siyuan Ma, Hairuo Lin, Xiaokang Fu, Rui Zhang, Jianping Bin, Yulin Liao, Qiancheng Wang   +12 more
wiley   +1 more source

Advances and challenges in research methods on oral absorption mechanisms of nano-formulations. [PDF]

PeerJ
Sun SJ, Liu YT, Nie JY, Hu ZY, Liu ZR, Chen H, Hua YZ, Feng S, Yi T, Zhang JF.   +9 more
europepmc   +1 more source

A Simplified Risk Assessment Tool to Predict Post Deceased Donor Liver Transplantation Outcomes: A Single, Highly Experienced Medical Center in Taiwan

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Liver transplantation (LT) is the standard treatment for end‐stage liver disease, yet the gap between the demand for organs and their availability is widening. In Taiwan, the scarcity of deceased donor organs highlights the need for optimized utilization strategies.
Jie‐Lan Jhang, Hao‐Chien Hung, Yin Lai, Jin‐Chiao Lee, Yu‐Chao Wang, Chih‐Hsien Cheng, Tsung‐Han Wu, Chen‐Fang Lee, Ting‐Jung Wu, Hong‐Shiue Chou, Kun‐Ming Chan, Wei‐Chen Lee   +11 more
wiley   +1 more source

Beyond the Watershed: Chronic Ischemic Colitis Masking Underlying Small Bowel Non-Hodgkin Lymphoma. [PDF]

Cureus
Khan H, Hamadah Y, Jani A, Dsouza A, Baldwin J.   +4 more
europepmc   +1 more source