Results 151 to 160 of about 120,404,711 (181)
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Journal of Asian Natural Products Research, 2017
The purpose of this study was to investigate the absorption properties of isorhamnetin (IS), quercetin (QU), and kaempferol (KA) in total flavones of Hippophaë rhamnoides L. (TFH) by an in situ single-pass intestinal perfusion model. The results indicated that IS, QU, and KA in TFH were absorbed site-dependently, and both enterohepatic circulation and ...
Lei, Xin +6 more
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The purpose of this study was to investigate the absorption properties of isorhamnetin (IS), quercetin (QU), and kaempferol (KA) in total flavones of Hippophaë rhamnoides L. (TFH) by an in situ single-pass intestinal perfusion model. The results indicated that IS, QU, and KA in TFH were absorbed site-dependently, and both enterohepatic circulation and ...
Lei, Xin +6 more
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Journal of Chromatography B, 2004
A simple, sensitive and specific reversed-phase high performance liquid chromatographic (RP-HPLC) assay for simultaneous determination of digoxin and permeability markers, in samples obtained from intestinal in situ single-pass perfusion studies, was developed and validated.
Manthena V S, Varma +3 more
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A simple, sensitive and specific reversed-phase high performance liquid chromatographic (RP-HPLC) assay for simultaneous determination of digoxin and permeability markers, in samples obtained from intestinal in situ single-pass perfusion studies, was developed and validated.
Manthena V S, Varma +3 more
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Pharmaceutical Research, 1997
A permeability-index approach was developed and used to study the transport of D-glucose in the jejunum and ileum of rats.The effective permeability coefficient (Pe) of [3H]D-glucose and [14C]antipyrine (an internal standard) in jejunum and ileum of four rats was determined using an in situ rat intestinal perfusion technique.
Y, Wang, R, Aun, F L, Tse
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A permeability-index approach was developed and used to study the transport of D-glucose in the jejunum and ileum of rats.The effective permeability coefficient (Pe) of [3H]D-glucose and [14C]antipyrine (an internal standard) in jejunum and ileum of four rats was determined using an in situ rat intestinal perfusion technique.
Y, Wang, R, Aun, F L, Tse
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[Absorption of flavonoids from Abelmoschus manihot extract by in situ intestinal perfusion].
Yao xue xue bao = Acta pharmaceutica Sinica, 2013To explore the mechanism of the absorption of flavonoids from Abelmoschus manihot flowers, in situ intestinal recirculation was performed to study the effect of the absorption at different concentrations and different intestinal regions. To evaluate the conditions of the absorption of six flavonoids from Abelmoschus manihot flowers, the concentrations ...
Cai-fu, Xue +4 more
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China Journal of Chinese Materia Medica, 2011
Objective To study the absorption characteristics of alkaloids in Coptis chinensis in rat intestinal. Method In situ single-pass perfused rat intestinal model was used and the concentrations of berberine and palmatine were determined by HPLC, the drug absorption rate constant (K(a)) and apparent absorption coefficient (P(app)) were tested to ...
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Objective To study the absorption characteristics of alkaloids in Coptis chinensis in rat intestinal. Method In situ single-pass perfused rat intestinal model was used and the concentrations of berberine and palmatine were determined by HPLC, the drug absorption rate constant (K(a)) and apparent absorption coefficient (P(app)) were tested to ...
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In situ Single-Pass Perfused Rabbit Intestinal Study sample Analysis of Ractopamine by UPLC
Asian Journal of Research in Pharmaceutical SciencesIn recent years, the prediction of oral drug absorption in humans has been a challenge for researchers and many techniques for permeability studies have been developed for several purposes, including biowaiver processes. The Single-Pass Intestinal Perfusion (SPIP) method performed in rats can provide permeability results closest to in vivo condition ...
Namzi, Fatima +2 more
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012
To study the absorption characteristics of alkaloids in Coptis chinensis in rat intestinal.In situ single-pass perfused rat intestinal model was used and the concentrations of berberine and palmatine were determined by HPLC, the drug absorption rate constant (K(a)) and apparent absorption coefficient (P(app)) were tested to evaluate their absorption ...
Ying, Chen +7 more
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To study the absorption characteristics of alkaloids in Coptis chinensis in rat intestinal.In situ single-pass perfused rat intestinal model was used and the concentrations of berberine and palmatine were determined by HPLC, the drug absorption rate constant (K(a)) and apparent absorption coefficient (P(app)) were tested to evaluate their absorption ...
Ying, Chen +7 more
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Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2018
To investigate the overall intestinal permeability of multiple components in lotus leaves and make clear the interaction in composition absorption process. Rat single-pass intestinal perfusion technique was used, and the results showed that the Peff values of nuciferine, demethylanuciferine, rutin, quercetin, kaempferol from lotus leaf were greater ...
Xiu-Wen, Yin +6 more
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To investigate the overall intestinal permeability of multiple components in lotus leaves and make clear the interaction in composition absorption process. Rat single-pass intestinal perfusion technique was used, and the results showed that the Peff values of nuciferine, demethylanuciferine, rutin, quercetin, kaempferol from lotus leaf were greater ...
Xiu-Wen, Yin +6 more
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Vascular perfusion of rat small intestine: metabolic studies with isolated and in situ preparations.
Federation proceedings, 1977Two different preparations of vascularly-perfused rat small intestine are described and their application to metabolic studies in this tissue illustrated. The first, a totally isolated, blood-perfused intestinal preparation, has an apparent requirement for glucocorticoid and norepinephrine.
H G, Windmueller, A E, Spaeth
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