Results 71 to 80 of about 2,554,686 (233)
Bovine colostrum increases pore-forming claudin-2 protein expression but paradoxically not ion permeability possibly by a change of the intestinal cytokine milieu. [PDF]
PLoS ONE, 2013 An impaired intestinal barrier function is involved in the pathogenesis of inflammatory bowel disease (IBD). Several nutritional factors are supposed to be effective in IBD treatment but scientific data about the effects on the intestinal integrity ...
Peggy Bodammer +3 more
doaj +1 more source
Ex vivo normothermic perfusion of isolated segmental porcine bowel: a novel functional model of the small intestine. [PDF]
, 2021 BACKGROUND: There is an unmet need for suitable ex vivo large animal models in experimental gastroenterology and intestinal transplantation. This study details a reliable and effective technique for ex vivo normothermic perfusion (EVNP) of segmental ...
Barlow, AD +10 more
core +1 more source
Biomedicine & Pharmacotherapy, 2018 Araloside A is a triterpenoid saponin,which exhibits a broad spectrum of pharmacological activities, such as stimulating fibrinolysis, preventing coagulant, inhibiting renin, and decreasing blood pressure. Our previous report found that the compound exhibits a poor absolute bioavailability.
Jing Sun +6 more
openaire +3 more sources
International Journal of Integrated Health Sciences, 2018 Objective: To observe the effects of infused oyster mushroom (latin name: Pleurotus ostreatus) on glucose absorption through the intestinal mucosal membrane in Wistar rats. Methods: This study used experimental design. Subjects of this study were six
Eko Fuji Ariyanto +2 more
doaj +1 more source
INTESTINAL ABSORPTION OF EPROSARTAN MESYLATE FROM SELF EMULSIFYING SYSTEM AND CYCLODEXTRIN COMPLEX [PDF]
, 2017 Objective: The aim of this work was to determine the intestinal membrane transport parameters of eprosartan mesylate (EM) and to investigate self-nano emulsifying drug delivery systems (SNEDDS) and inclusion complexation with hydroxypropyl b cyclodextrin
El Maghraby, Gamal M. +2 more
core +1 more source
Comparison of intestinal permeability of nebivolol hydrochloride loaded solid lipid nanoparticles with commercial nebivolol tablet [PDF]
, 2018 WOS: 000458080300013The oral application of drugs is the most popular route for achieving systemic effects, nevertheless, it is limited by difficulties related to physicochemical properties of the drug.
Gökçe, Evren Homan +4 more
core +1 more source
Journal of Pharmacy & Pharmaceutical Sciences, 2008 Purpose.To determine the possible mechanism of poor bioavailability of bicyclol, and clarify the respective contribution of P- glycoprotein (P-gp) and Cytochrome 3A (CYP3A). Methods. Rat in situ single-pass intestinal perfusion and Caco-2 cell monolayer
Wei Tan, Hui Chen, Jinping Hu, Yan Li
doaj +1 more source
Acta Pharmaceutica Sinica B, 2014 The aim of this study was to develop a formulation to improve the oral absorption of baicalin (BA) by combining a phospholipid complex (PC) and self-emulsifying microemulsion drug delivery system (SMEDDS), termed BA–PC–SMEDDS.
Huiyi Wu +7 more
doaj +1 more source
A study on enhanced intestinal permeability of clarithromycin nanoparticles [PDF]
, 2014 The main objective of the present study was to determine the permeability of clarithromycin (CLA)-PLGA nanoparticles using single-pass intestinal perfusion technique in rats.
Islambulchilar, Ziba +5 more
core +3 more sources
Detection of perfusion ROI as a quality control in perfusion analysis [PDF]
in Proc. Science, Research, Development. Technics and Technology,
Berlin, Germany, Jan 30, 2018, pp.57-59, 2019 In perfusion analysis automated approaches for image processing is preferable due to reduce time-consuming tasks for radiologists. Assessment of perfusion results quality is important step in development of algorithms for automated processing. One of them is an assessment of perfusion maps quality based on detection of perfusion ROI.
arxiv