Results 11 to 20 of about 568,096 (301)
A surprisingly poor correlation between in vitro and in vivo testing of biomaterials for bone regeneration: results of a multicentre analysis [PDF]
European Cells & Materials, 2016 New regenerative materials and approaches need to be assessed through reliable and comparable methods for rapid translation to the clinic. There is a considerable need for proven in vitro assays that are able to reduce the burden on animal testing, by ...
G Hulsart-Billström +12 more
doaj +3 more sources
In vitro – in vivo correlation of intranasal drug deposition
Advanced Drug Delivery Reviews, 2021 In vitro - in vivo correlation (IVIVC) allows prediction of in vivo drug deposition from a nasally inhaled drug based on in vitro drug measurements. In vitro measurements include physical particle characterization and, more recently, deposition studies using anatomical models.
Le Guellec, S. +2 more
openaire +4 more sources
Percutaneous Absorption in Man: In vitro-in vivo Correlation [PDF]
Skin Pharmacology and Physiology, 2011 <i>Aims:</i> To examine the existing literature to determine the degree to which percutaneous absorption data obtained using the excised human skin model match those obtained from living man. <i>Methods:</i> The scientific literature was reviewed to collect data on compounds whose percutaneous absorption through human skin had ...
P A, Lehman, S G, Raney, T J, Franz
openaire +3 more sources
Frontiers in Pharmacology, 2023 Background: Essential medicine is a vital component to assure universal access to quality healthcare. However, the trend of affordability to essential medicines in China and its regional differences were not yet fully understood.
Zheng Liu +53 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Background: At present, only one systematic review has investigated the effect of levothyroxine (LT4) in the treatment of euthyroid pregnant women with thyroid autoimmunity, but some problems [such as merging different types of research for meta-analysis,
Jingjing Chen +37 more
doaj +1 more source
Frontiers in Endocrinology, 2022 BackgroundSeveral systematic reviews and meta-analyses have investigated the effect of levothyroxine (LT4) therapy in pregnant women with subclinical hypothyroidism (SCH).
Xue-Feng Jiao +40 more
doaj +1 more source
Frontiers in Public Health, 2023 BackgroundEssential medicines are the backbone of healthcare and meet the priority healthcare needs of the population. However, approximately one-third of the global population does not have access to essential medicines.
Miao Zhang +54 more
doaj +1 more source
A tool for screening potentially inappropriate prescribing in Chinese children
Frontiers in Pharmacology, 2022 Background: More than half of adverse drug events in pediatric patients are avoidable and blocking medication errors at the prescribing stage might be one of the most effective preventive measures.Objective: To form a tool (a series of criteria) for ...
Siyu Li +25 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Background: The role of antihypertensive drugs in inducing hyperuricaemia and gout has been a long-term concern in clinical practice. However, clinical studies regarding this issue are limited in number and have yielded inconsistent results.
Xue-Feng Jiao +25 more
doaj +1 more source
Physiologically Relevant In Vitro-In Vivo Correlation (IVIVC) Approach for Sildenafil with Site-Dependent Dissolution. [PDF]
Pharmaceutics, 2019 Kim TH +4 more
europepmc +2 more sources