Florfenicol sustained-release granules: an in vitro-in vivo correlation study in pigs [PDF]
BMC Veterinary Research, 2023 The objective of this study was to synthesize and characterize pharmaceutical characteristics of florfenicol sustained-release granules (FSRGs) in vitro and in vivo. FSRGs were synthesized using monostearate, polyethylene glycol 4000 and starch. In vitro
Wei-cong Yang +6 more
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Developing In Vitro–In Vivo Correlation for Bicalutamide Immediate-Release Dosage Forms with the Biphasic In Vitro Dissolution Test [PDF]
PharmaceuticsBackground/Objectives: Reflecting the interaction between dissolution and absorption, the biphasic dissolution system is an appealing approach for estimating the intestinal absorption of drugs in humans.
Nihal Tugce Ozaksun, Tuba Incecayir
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In Vitro–In Vivo Correlation of Tianeptine Sodium Sustained-Release Dual-Layer Tablets [PDF]
Molecules, 2022 Tianeptine tablets are currently marketed to be designed for immediate-release tablets. The tianeptine has a short half-life, making it difficult to design for sustained-release tablets and achieve bioequivalence with the tianeptine immediate-release ...
Ye-Ji Lee, Joo-Eun Kim
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Improving In Vitro–In Vivo Correlation (IVIVC) for Lipid-Based Formulations: Overcoming Challenges and Exploring Opportunities [PDF]
PharmaceuticsLipid-based formulations (LBFs) play a crucial role in enhancing the oral bioavailability of poorly water-soluble drugs by leveraging lipid digestion and solubilization processes. However, developing robust in vitro–in vivo correlations (IVIVCs) for LBFs
Arnaud Bourderi-Cambon +7 more
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Franz Cell Diffusion Testing and Quantitative Confocal Raman Spectroscopy: In Vitro-In Vivo Correlation [PDF]
Pharmaceutics, 2020 Previously, we reported the use of Confocal Raman Spectroscopy (CRS) to investigate the topical delivery of actives and excipients. We have also correlated the results from CRS with findings from in vitro diffusion studies in human skin.
Fotis Iliopoulos +3 more
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Pharmaceutics, 2020 This study optimized the preparation of electrosprayed microspheres containing leuprolide and developed an in vitro−in vivo correlation (IVIVC) model that enables mutual prediction between in vitro and in vivo dissolution.
Dong-Seok Lee +4 more
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In Vitro–In Vivo Correlation (IVIVC) Population Modeling for the In Silico Bioequivalence of a Long-Acting Release Formulation of Progesterone [PDF]
Pharmaceutics, 2021 Elena Maria Tosca +2 more
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Research on prescribing cascades: a scoping review
Frontiers in Pharmacology, 2023 Background: The concept of prescribing cascades has been proposed for more than 20 years, but the research progress and cognitive level varied in different countries.
Zhe Chen +22 more
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Frontiers in Pharmacology, 2023 Background: Essential medicine is a vital component to assure universal access to quality healthcare. However, the trend of affordability to essential medicines in China and its regional differences were not yet fully understood.
Zheng Liu +53 more
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Frontiers in Pharmacology, 2023 Background: At present, only one systematic review has investigated the effect of levothyroxine (LT4) in the treatment of euthyroid pregnant women with thyroid autoimmunity, but some problems [such as merging different types of research for meta-analysis,
Jingjing Chen +37 more
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