Results 11 to 20 of about 535,121 (211)

The impact of levothyroxine therapy on the pregnancy, neonatal and childhood outcomes of subclinical hypothyroidism during pregnancy: An updated systematic review, meta-analysis and trial sequential analysis

open access: yesFrontiers in Endocrinology, 2022
BackgroundSeveral systematic reviews and meta-analyses have investigated the effect of levothyroxine (LT4) therapy in pregnant women with subclinical hypothyroidism (SCH).
Xue-Feng Jiao   +40 more
doaj   +1 more source

Availability of essential medicines, progress and regional distribution in China: a systematic review and meta-analysis

open access: yesFrontiers in Public Health, 2023
BackgroundEssential medicines are the backbone of healthcare and meet the priority healthcare needs of the population. However, approximately one-third of the global population does not have access to essential medicines.
Miao Zhang   +54 more
doaj   +1 more source

A tool for screening potentially inappropriate prescribing in Chinese children

open access: yesFrontiers in Pharmacology, 2022
Background: More than half of adverse drug events in pediatric patients are avoidable and blocking medication errors at the prescribing stage might be one of the most effective preventive measures.Objective: To form a tool (a series of criteria) for ...
Siyu Li   +25 more
doaj   +1 more source

Hyperuricaemia, gout and related adverse events associated with antihypertensive drugs: A real-world analysis using the FDA adverse event reporting system

open access: yesFrontiers in Pharmacology, 2023
Background: The role of antihypertensive drugs in inducing hyperuricaemia and gout has been a long-term concern in clinical practice. However, clinical studies regarding this issue are limited in number and have yielded inconsistent results.
Xue-Feng Jiao   +25 more
doaj   +1 more source

Long-term economic evaluation of the recombinant Mycobacterium tuberculosis fusion protein (EC) test for the diagnosis of Mycobacterium tuberculosis infection

open access: yesFrontiers in Pharmacology, 2023
Background: Tuberculosis continues to be a significant global burden. Purified protein derivative of tuberculin (TB-PPD) is one type of tuberculin skin test (TST) and is used commonly for the auxiliary diagnosis of tuberculosis.
Sha Diao   +50 more
doaj   +1 more source

Recombinant mycobacterium tuberculosis fusion protein for diagnosis of mycobacterium tuberculosis infection: a short-term economic evaluation

open access: yesFrontiers in Public Health, 2023
ObjectivesRecombinant Mycobacterium tuberculosis fusion protein (EC) was anticipated to be used for the scale-up of clinical application for diagnosis of Mycobacterium tuberculosis infection in China, but it lacked a head-to-head economic evaluation ...
Zheng Liu   +50 more
doaj   +1 more source

Accessibility of essential anticancer medicines for children in the Sichuan Province of China

open access: yesFrontiers in Public Health, 2022
BackgroundCompared with high-income countries, the survival rate of childhood cancer is lower in low- and middle-income countries. Access to essential anticancer medicines is an indispensable component of pediatric cancer treatment, which is still a big ...
Zhe Chen   +35 more
doaj   +1 more source

Effectiveness and safety of Lacosamide therapy for children with focal epilepsy: a real world study

open access: yesFrontiers in Pharmacology, 2023
Objectives: To compare the effectiveness and safety of the new antiepileptic drug, lacosamide (LCM) with Levetiracetam, for the treatment of focal epilepsy in children.Methods: This study was a cohort study.
Chunsong Yang   +16 more
doaj   +1 more source

Estimation of the In Vivo Release of Amiodarone From the Pharmacokinetics of Its Active Metabolite and Correlation With Its In Vitro Release

open access: yesFrontiers in Pharmacology, 2021
Due to its very low water solubility and complex pharmacokinetics, a reliable point-to-point correlation of its in vitro release with its pharmacokinetics has not been achieved so far with amiodarone. The correlation of the in vitro dissolution of a drug
Maytham Razaq Shleghm   +4 more
doaj   +1 more source

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