Results 111 to 120 of about 6,403,737 (347)

Human Naive CD8 T Cells Down-Regulate Expression of the WNT Pathway Transcription Factors Lymphoid Enhancer Binding Factor 1 and Transcription Factor 7 (T Cell Factor-1) following Antigen Encounter In Vitro and In Vivo [PDF]

, 2006
Tim Willinger, Tom C. Freeman, Mark Herbert, Hitoshi Hasegawa, Andrew J. McMichael, Margaret Callan   +5 more
openalex   +1 more source

Synthetic in vitro transcriptional oscillators [PDF]

, 2011
The construction of synthetic biochemical circuits from simple components illuminates how complex behaviors can arise in chemistry and builds a foundation for future biological technologies.
Kim, Jongmin, Winfree, Erik
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

A human relevant in vitro alveolar epithelial barrier model to assess inhaled pollutant hazard

Scientific Reports
Relevant in vitro models could reduce the requirement for in vivo testing and allow higher throughput for imperative toxicological or pharmaceutical hazard testing.
Joshua W. P. Bateman, Kirsty Meldrum, Sarah M. Mitchell, Ulla Vogel, Martin J. D. Clift   +4 more
doaj   +1 more source

In Vitro Studies on Pollen Viability, Pollen Germination and Pollen Tube Growth of Hornstedtia Conoidea Ridl. – a Philippine Endemic Ginger Species [PDF]

, 2018
Zingiberaceous plants are predominantly propagated through underground rhizomes and seeds. In this study, the viability of pollen, rate of pollen germination and length of pollen tube of the Philippine endemic Hornstedtia conoidea were examined.
Acma, F. M. (Florfe), Mendez, N. P. (Noe)   +1 more
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Atividade nematicida in vitro de resíduos agroindustriais. [PDF]

, 2014
O trabalho objetivou avaliar a atividade nematicida de extratos da torta de mamona e do bagaço de uva, resíduos agroindustriais da produção de biodiesel e vinho ...
ANDRADE, L. B. da S., BRAGA, A. C. L., CAVALCANTE, A. C. R., SALLES, H. O., SOUSA, A. M. P., VIEIRA, L. da S., VOLTOLINI, T. V.   +6 more
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Molecular Identification of Human and Plant Pathogens in Municipal Domestic Wastewater for Hydroponic System Applications

International Journal of Microbiology
Water is essential for human survival and socioeconomic development, yet its overconsumption threatens global food security and ecosystem integrity. This necessitates a 60% increase in food production, further straining water resources.
Lukas Simon Kriem, Neil King, Sinja Niemann, Yevhen Vainshtein, Mirko Sonntag   +4 more
doaj   +1 more source

In Vitro Rooting of Poplar: Effects and Metabolism of Dichlorprop Auxin Ester Prodrugs

Plants
Efficient adventitious root formation is essential in micropropagation. Auxin prodrugs, inactive precursors that convert into active auxins within the plant, offer potentially improved rooting control and reduced phytotoxicity.
Hajer Darouez, Stefaan P. O. Werbrouck
doaj   +1 more source