Results 121 to 130 of about 7,982,325 (356)

In-vitro Degradation Behaviour of Irradiated Bacterial Cellulose Membrane [PDF]

open access: yes, 2012
Bacterial cellulose membrane synthesized by Acetobacter xylinum in coconut water medium has potential application for Guided bone Regeneration. However, this membrane may not meet some application requirements due to its low biodegradation properties. In
Darwis, D. (D)   +4 more
core  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Comparação entre vitrificação e congelamento lento sobre o desenvolvimento pós-descongelamento de embriões bovinos produzidos in vitro

open access: yesSemina: Ciências Agrárias
Avaliou-se o desenvolvimento pós-descongelamento de embriões bovinos produzidos in vitro (PIV) criopreservados pela técnica de vitrificação e de congelamento lento em diferentes dias após a fertilização in vitro (FIV). Foram realizadas 9 réplicas de PIV.
Vanessa Rachele Ribeiro Nunes   +5 more
doaj   +1 more source

Induksi In Vitro Tanaman Gaharu (Aquilaria Microcarpa Baill.) dari Eksplan Tunas Aksilar dengan Penambahan 6-benzylaminopurine (Bap) [PDF]

open access: yes, 2014
Aquilaria microcarpa Baill. can produce agarwood products that can be used for various purposes, therefore it can caus a high demand for the product. Nowadays, these species are being hunted in their natural habitats.
Lestari, W. (Wahyu)   +2 more
core  

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

open access: yesMolecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric   +11 more
wiley   +1 more source

In-vitro Evaluation of Botanicals, Fungi-toxic Chemicals and Bio-control Agent for Efficacy Against Turcicum Leaf Blight of Maize [PDF]

open access: yes, 2019
Maize is the second most important cereal crop of Nepal. Its growth and production is severely affected by Turcicum leaf blight caused by Exserohilum turcicum at pre-harvest stage.
BK, S. (Surendra)   +3 more
core  

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

Cost-effectiveness of short COH protocols with GnRH antagonists using different types of gonadotropins for in vitro fertilization

open access: yesBiotechnology & Biotechnological Equipment, 2016
The aim of this study was to explore the cost-effectiveness of short protocols including different types of gonadotropins for controlled ovarian hyperstimulation (COH) for in vitro fertilization (IVF).
Guenka Petrova   +5 more
doaj   +1 more source

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