Lipid droplets in granulosa cells are correlated with reduced pregnancy rates
Background Lipids are an important source for energy production during oocyte maturation. The accumulation of intracellular lipids binds to proteins to form lipid droplets. This may lead to cellular lipotoxicity. The impact of lipotoxicity on cumulus and
Shira Raviv +5 more
doaj +1 more source
Does seminal fluid bacterial isolate(s) affect in vitro fertilization — embryo transfer outcome?
Background The chance of achieving a successful pregnancy through in vitro fertilization and embryo transfer (IVF-ET) is limited despite recent scientific advances in this field due to several factors that are known to affect the outcome.
Rukayya Muhammad Babandi +5 more
doaj +1 more source
Changes in acetylation of lysine 5 on histone H4 in canine oocytes following in vitro maturation [PDF]
Post-translational modifications of histones, such as acetylation, are involved in regulating chromatin remodelling and gene expression. Proper in vitro maturation (IVM) of canine oocytes, for many reasons, is up to now inefficient.
Alves, A. E. +7 more
core +1 more source
Genotoxicity testing in vitro - development of a higher throughput analysis method based on the comet assay [PDF]
S.1570-1575Higher throughput methods, high content analysis and automated screening methods are of highest demand in drug development today. In toxicology, these strategies are becoming increasingly important, as well.
Ritter, D., Knebel, J.
core +1 more source
Background and aims: Non-alcoholic steatohepatitis (NASH) is a life-threatening stage of non-alcoholic fatty liver disease (NAFLD) for which no drugs have been approved.
Joost Boeckmans +7 more
doaj +1 more source
Effects of nicotine, its metabolites and tobacco extracts on human platelet function in vitro [PDF]
Cigarette smoking is a leading cause of cardiovascular disease. The cardiovascular effects of smoking are probably multifactorial, including effects on platelets. Previous reports investigating the effects of nicotine and tobacco on platelet function are
Eriksson, Andreas +15 more
core +1 more source
In Vitro Antibiotic Susceptibilities of Ocular Isolates in North and South America [PDF]
PURPOSETo assess the in vitro susceptibility of ocular bacterial isolates from North and South America to antiinfectives that are commonly used in the treatment of external ocular infection.
In Vitro Antibiotic Testing Grp +2 more
core +1 more source
A rise in serum progesterone in the late follicular phase is a well described adverse effect of ovarian stimulation for IVF/ICSI. Previous data suggest, that enhanced gonadotropin stimulation causes progesterone elevation and the incidence of premature ...
Barbara Lawrenz +7 more
doaj +1 more source
Direct comparison between in vivo and in vitro microsized particle phagocytosis assays in Drosophila melanogaster [PDF]
The effects of micro and nanoparticles on the innate immune system have been widely investigated and a general lack of agreement between in vivo and in vitro assays has been observed.
Prinz, C. N., +6 more
core +1 more source
Supplementation with sunflower seeds in beef cattle did not impact on oocyte and in vitro embryo production [PDF]
Supplementation with compounds rich in linoleic acid, including sunflower seed supplementation, promotes increase in conception rates in cows. We aimed to evaluate whether the sunflower seed (linoleic acid source) supplementation in beef donor females ...
Baltazar, A. L. [UNESP] +11 more
core +1 more source

