Results 251 to 260 of about 88,172 (307)
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In Vitro Dissolution of Cholesterol Gallstones
Investigative Radiology, 1992Methyl tert-butyl ether (MTBE) is the solvent most commonly used for in vivo dissolution of cholesterol gallstones. Its limitations, however, include high volatility and flammability along with potential toxicologic concerns. Therapy may take several hours.
R S, Sternal, M A, Davis
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In vitro dissolution of piroxicam capsules
Journal of Clinical Pharmacy and Therapeutics, 1994The in vitro dissolution rates of 10- and 20-mg piroxicam capsules from different suppliers in the U.K. were measured in simulated gastric fluid using rotating basket apparatus. Seven brands were tested and all were found to be satisfactory with at least 75% dissolution in 45 min.
A C, Mehta, S, Hart-Davies
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In Vitro Dissolution of Uranium
Radiation Protection Dosimetry, 1994As part of the recommended procedure for calculating radiation doses from inhaled radioactive material, the ICRP divides radionuclides into three transportability classes on the basis of their dissolution half-times. A method of measuring dissolution rates of uranium compounds in lung fluid using a batch replacement method has been commonly used to ...
P.J. Cusbert, M.W. Carter, D.A. Woods
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Dissolution Testing of Sublingual Tablets: A Novel In Vitro Method
AAPS PharmSciTech, 2011 In the sublingual (SL) cavity, compared with the gastrointestinal tract, tablets are subjected to minimal physiological agitation, and a limited volume of saliva is available to facilitate disintegration and dissolution.
Ousama Rachid +2 more
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Dissolution test for citalopram in tablets and comparison of in vitro dissolution profiles
European Journal of Pharmaceutics and Biopharmaceutics, 2007A dissolution test for tablets containing 20 mg of citalopram was developed and validated using a reverse-phase liquid chromatographic method and this dissolution test was applied to compare dissolution profiles. The sink conditions, filters, stability of the drug and specificity on different dissolution media were tested to choose a discriminatory ...
Júlia, Menegola +2 more
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In Vitro Dissolution of Cystine Urinary Calculi
Journal of Urology, 1986Dissolution of cystine urinary calculi was studied in vitro. Sodium hydroxide, acetylcysteine and tris(hydroxymethyl)aminomethane (tromethamine) were tested for effectiveness in dissolving cystine calculi. Calculi were mounted in a dissolution apparatus.
J R, Burns, L C, Hamrick
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Chemical Dissolution of Gallstones: In Vitro Studies
Radiology, 1989Groups of human cholesterol gallstones were subjected to monooctanoin with and without agitation, methyl-tert-butyl ether (MTBE) with and without agitation, and monooctanoin and MTBE used in succession with agitation. In this in vitro study, agitation greatly expedited the rate of dissolution with MTBE, by far the more potent of the two solvents.
J H, Oldershaw +3 more
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Dissolution profiles of mesalazine formulationsin vitro
Pharmaceutisch Weekblad Scientific Edition, 1990In vitro dissolution profiles of three controlled-release mesalazine formulations were determined at pH 1.0, 6.0 and 7.5. A closed-column type dissolution apparatus was used. A reproducible gradual dissolution profile was seen for Pentasa at all pH values. Dissolution starts immediately and is complete after 20 h.
L M, Stolk +3 more
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In vitro dissolution of calcium carbonate preparations
Calcified Tissue International, 1991Calcium supplements are widely used for the treatment of osteoporosis. The bioavailability of these preparations is unknown. Because poor tablet dissolution accounts for a majority of drug bioavailability problems, we determined the in vitro dissolution at 30, 60, and 90 minutes of 27 commercially available calcium carbonate supplements using the ...
M J, Brennan +4 more
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In vitro dissolution studies on nifedipine capsules
Journal of Clinical Pharmacy and Therapeutics, 1995The in vitro dissolution rates of 5 and 10 mg nifedipine capsules from eight suppliers were measured in simulated gastric fluid using the rotating paddle apparatus. A total of fourteen products were tested and the performance was found to be satisfactory for all products (> 80% dissolution in 20 min).
A C, Mehta, S, Hart-Davies, E A, Kay
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