Results 261 to 270 of about 88,172 (307)

New In Vitro Dissolution Test Apparatus

Journal of Pharmaceutical Sciences, 1979
A new in vitro dissolution test apparatus was designed and evaluated. Compressed tablets of drugs representing different solubility characteristics were tested at various air pressures and compared to dissolution patterns of similar tablets by the Levy beaker and USP methods.
S S, Nasir, L O, Wilken, S M, Nasir
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In vitro investigation on cinnabar dissolution

Frontiers of Chemistry in China, 2007
To study the effects of different chemical factors in the gastrointestinal tract, i.e. pH, proteins, amino acids, ionic strength and Na2S, on the dissolution of cinnabar. The content of the total mercury in various dissolutions of cinnabar was analyzed by UV/VIS Spectrophotometer.
Kewu Zeng, Qi Wang, Xiaoda Yang, Kui Wang   +3 more
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An evaluation of fit factors and dissolution efficiency for the comparison of in vitro dissolution profiles

Journal of Pharmaceutical and Biomedical Analysis, 1998
Dissolution efficiency (D.E.), the area under a dissolution curve between defined time points, and the fit factors (f1 and f2) have been compared for the characterisation of dissolution profiles, using data from three batches of a product in nine different packs stored under two conditions.
N H, Anderson, M, Bauer, N, Boussac, R, Khan-Malek, P, Munden, M, Sardaro   +5 more
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Standardization of in vitro dissolution assays

International Journal of Pharmaceutics, 1983
Abstract A previous communication by Konieczny et al. (1980) has high-lighted the advantages of determining the dissolution rate of both a test sample and a control, or reference lot of the formulation, at the same time in the same equipment. One can immediately reject aberrant test sample values or normalize the test sample results by comparison ...
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In Vitro- In Vivo Correlation’s Dissolution Limits Setting

Pharmaceutical Research, 2014
In vitro in vivo correlation (IVIVC) is a biopharmaceutical tool recommended for use in formulation development. When validated, IVIVC can be used to set dissolution limits and, based on the dissolution limits, as a surrogate for an in vivo study.
B, Roudier, B M, Davit, E, Beyssac, J-M, Cardot   +3 more
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Simultaneous determination of dissolution and partitioning rates in vitro

Journal of Pharmaceutical Sciences, 1967
An in vitro method is presented for the simultaneous determination of the dissolution and partitioning rates of drugs. The kinetics of the system is described, and a number of methods are given for evaluating the rate constants. The effects of stirring rate and temperature upon the rate constants were investigated and found to be in agreement with ...
P J, Niebergall, M Y, Patil, E T, Sugita
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In-Vitro Drug Dissolution Studies in Medicinal Compounds

Current Medicinal Chemistry, 2018
After oral administration, drug absorption from solid dosage forms depends on the release of the drug active compounds from the dosage form, the dissolution or solubilization of the drug under physiological conditions, and the permeability across the gastrointestinal tract.
Burcin, Bozal-Palabiyik, Bengi, Uslu, Yalcin, Ozkan, Sibel A, Ozkan   +3 more
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Preparation and in vitro dissolution of magnolol solid dispersion

China Journal of Chinese Materia Medica, 2016
In this study, solid dispersion system of magnolol in croscarmellose sodium was prepared by using the solvent evaporation method, in order to increase the drug dissolution. And its dissolution behavior, stability and physical characteristics were studied.
Lan, Tang, Shuai-Bo, Qiu, Lan, Wu, Long-Fei, Lv, Hui-Xia, Lv, Wei-Guang, Shan   +5 more
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In Vitro Dissolution Testing of Drug-Eluting Stents

Current Pharmaceutical Biotechnology, 2013
Drug-eluting stents (DES) have revolutionized the treatment of coronary artery blockage by tremendously reducing the rate of in-stent restenosis and the necessity of repeat revascularization compared to bare-metal stents. They are also gaining increasing importance in other medical fields such as the treatment of certain localized tumors and in ...
Anne, Seidlitz, Stefan, Nagel, Beatrice, Semmling, Katrin, Sternberg, Heyo K, Kroemer, Werner, Weitschies   +5 more
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Perspectives of in vitro dissolution tests in establishing in vivo/in vitro correlations

European Journal of Drug Metabolism and Pharmacokinetics, 1993
Perspectives of in vitro dissolution tests in establishing an in vivo/in vitro correlation are considered at three different levels. The first involves the selection of a drug product, or suitable batch(es), for the correlation study. This requires evaluation of the biopharmaceutical properties of the proposed drug from a profile compiled from a set of
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