Results 61 to 70 of about 670,418 (378)

CD137+CD154− Expression As a Regulatory T Cell (Treg)-Specific Activation Signature for Identification and Sorting of Stable Human Tregs from In Vitro Expansion Cultures

Frontiers in Immunology, 2018
Regulatory T cells (Tregs) are an attractive therapeutic tool for several different immune pathologies. Therapeutic Treg application often requires prolonged in vitro culture to generate sufficient Treg numbers or to optimize their functionality, e.g ...
A. Nowak, Dominik Lock, P. Bacher, Thordis Hohnstein, K. Vogt, Judith Gottfreund, Pascal Giehr, J. Polansky, B. Sawitzki, A. Kaiser, J. Walter, A. Scheffold   +11 more
semanticscholar   +1 more source

Long-Term Expansion of Porcine Intestinal Organoids Serves as an in vitro Model for Swine Enteric Coronavirus Infection

Frontiers in Microbiology, 2022
A reliable and reproducible model in vitro for swine enteric coronaviruses infection would be intestinal models that support virus replication and can be long-term cultured and manipulated experimentally.
Min Zhang, Lilei Lv, H. Cai, Yanhua Li, Fei Gao, Lingxue Yu, Yi-feng Jiang, Wu Tong, Li-wei Li, Guo-xin Li, G. Tong, Changlong Liu   +11 more
semanticscholar   +1 more source

Perfusion Cell Seeding and Expansion in Dual Mechanical Stimulation Bioreactor for In Vitro Tissue Development [PDF]

, 2020
BACKGROUND: Engineered tissues are an exciting potential source of small diameter vascular grafts due to limited supply and patency of available alternatives.
Coles, Sam, Saunders, Sarah, Soares, Joao S.   +2 more
core   +1 more source

In vitro expansion of human peripheral blood CD34+ cells [PDF]

Blood, 1993
To elucidate the role of recombinant human colony-stimulating factors (CSFs) for expanding peripheral blood (PB) CD34+ cells, these cells were purified up to 94.5% +/- 1.3% and the effects of individual and combined CSFs on the proliferation and differentiation of these cells were studied in a 7-day suspension culture.
N, Sato, K, Sawada, K, Koizumi, T, Tarumi, M, Ieko, T, Yasukouchi, M, Yamaguchi, T A, Takahashi, S, Sekiguchi, T, Koike   +9 more
openaire   +3 more sources

Robust Three-Dimensional (3D) Expansion of Bovine Intestinal Organoids: An In Vitro Model as a Potential Alternative to an In Vivo System

Animals, 2021
Simple Summary The ability to recapitulate stem cells’ self-organising potential, creating three-dimensional (3D) structures of stem cells, has revolutionised various fields.
B. Lee, Hyeon Yang, Sang-In Lee, I. Haq, S. Ock, Hayeon Wi, Hwi-Cheul Lee, Poongyeon Lee, J. Yoo   +8 more
semanticscholar   +1 more source

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis [PDF]

, 2014
Although hematopoietic precursor activity can be generated in vitro from human embryonic stem cells, there is no solid evidence for the appearance of multipotent, self-renewing and transplantable hematopoietic stem cells.
De Bleser, Dominique, De Mulder, Katrien, Kerre, Tessa, Lambrecht, Bart, Leclercq, Georges, Menten, Björn, Philippé, Jan, Taghon, Tom, Van Caeneghem, Yasmine, Van Roy, Nadine, Vandekerckhove, Bart, Vanhee, Stijn, Velghe, Imke, Verstichel, Greet   +13 more
core   +3 more sources

Role of echography in diagnostic dilemma in choroidal masses

Indian Journal of Ophthalmology, 2014
Purpose: To evaluate the role of echography in diagnosis and management of a diverse array of choroidal masses. Materials and Methods: Sixty-two cases of clinically suspected choroidal masses were prospectively analyzed with B-scan (10 Hz), A-scan, and ...
Kopal N Mithal, Hansa H Thakkar, Mudit A Tyagi, Rekha M Bharwada, Puja O Billore   +4 more
doaj   +1 more source

Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy [PDF]

, 2014
Cell-based regenerative therapies, based on in vitro propagation of stem cells, offer tremendous hope to many individuals suffering from degenerative diseases that were previously deemed untreatable.
Abu Kasim, N. H., Alabsi, A. M., Haque, N., Rahman, M. T.   +3 more
core   +1 more source

Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda

Nature Medicine, 2020
Artemisinin resistance (delayed P. falciparum clearance following artemisinin-based combination therapy), is widespread across Southeast Asia but to date has not been reported in Africa1–4. Here we genotyped the P.
A. Uwimana, E. Legrand, Barbara H. Stokes, Jean-Louis Mangala Ndikumana, M. Warsame, Noella Umulisa, D. Ngamije, Tharcisse Munyaneza, J. Mazarati, Kaendi J. Munguti, P. Campagne, A. Criscuolo, F. Ariey, Monique Murindahabi, P. Ringwald, D. Fidock, A. Mbituyumuremyi, D. Ménard   +17 more
semanticscholar   +1 more source

An optimized method for isolating and expanding invariant natural killer T cells from mouse spleen [PDF]

, 2015
The ability to rapidly secrete cytokines upon stimulation is a functional characteristic of the invariant natural killer T (iNKT) cell lineage. iNKT cells are therefore characterized as an innate T cell population capable of activating and steering ...
Drennan, Michael, Elewaut, Dirk, Govindarajan, Srinath   +2 more
core   +1 more source