Results 131 to 140 of about 377,852 (303)

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

open access: yesAdvanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti   +27 more
wiley   +1 more source

Regression Models for Estimating Fat Carcass Percentage Using Chest Measurement in Thin Tailed Lambs [PDF]

open access: yes, 2017
This study was conducted to evaluate the possibility of using chest measurement for subcutaneous, intermuscular, and total fat percentage in Thin Tailed Lambs.
Agung, Purnomoadi   +7 more
core  

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang   +13 more
wiley   +1 more source

Effect of mangosteen peel extract (Garcinia mangostana L.) supplementation on the in vitro gas kinetics, degradability, and intestinal digestion of proteins using a three-step in vitro procedure

open access: yesFrontiers in Animal Science
This study aimed to investigate the effect of tannin extract from mangosteen peel (MANGTAN) in soybean meal on the in vitro gas production kinetics, degradability, and intestinal digestion of proteins using a three-step in vitro procedure.
Chutikan Sonthongdaeng   +4 more
doaj   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec   +5 more
wiley   +1 more source

Yellow serofluid-inclusion enhanced anaerobic preservation of whole plant maize for subsequently reducing potential methane emission during in vitro ruminal fermentation

open access: yesBMC Microbiology
Yellow serofluid, a wine industry by-product, may alter microbial communities, enhance fermentation, and reduce methane emissions from ruminal fermentation.
Guangrou Lu   +9 more
doaj   +1 more source

Comparative anti-methanogenic ability of green algae (C. reinhardtii) with/without nanoparticles: in vitro gas and methane production

open access: yesFrontiers in Veterinary Science
IntroductionThe purpose of this study was to investigate how in vitro gas production (GP) and ruminal fermentation characteristics were affected by increasing concentrations of green algae plant (C. reinhardtii) extracts in combination with nanoparticles
Valiollah Palangi   +8 more
doaj   +1 more source

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