Results 181 to 190 of about 25,545 (268)

An engineered epididymal cell line provides a sustainable source of functional extracellular vesicles for in vitro sperm preservation: A multi‐omics and functional study

open access: yesVIEW, Volume 7, Issue 2, April 2026.
Schematic representation of the contribution of EVs proteins secreted by successfully established pEECs to sperm. pEECs‐derived EVs support sperm preservation in vitro through improved antioxidant capacity and viability, accompanied by reduced oxidative damage to membranes, mitochondria, DNA integrity and cell death.
Long Li   +10 more
wiley   +1 more source

Escherichia coli Nissle 1917 Occupies Previously Undocumented Host Niches in the Insect‐Parasitic Nematode Steinernema hermaphroditum

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 2, April 2026.
This study characterizes previously undocumented host tissues in Steinernema nematodes, including putative coelomocytes, intestinal compartments, and inter‐cuticular spaces colonized by Escherichia coli Nissle 1917. Our findings reveal niche‐specific microbial interactions distinct from those with native symbionts, establishing a platform for ...
Victoria Chen   +3 more
wiley   +1 more source

Unraveling the Genetic Mysteries of Müllerian Anomalies: Research Approaches and Clinical Significance

open access: yesClinical Genetics, Volume 109, Issue 4, Page 615-629, April 2026.
This review primarily summarizes the genetic defects in Müllerian anomalies, the tools used to validate these genetic defects, and the future clinical significance of identifying the precise genetic etiology of Müllerian anomalies. ABSTRACT Müllerian anomalies are a collection of heterogeneous anatomical disorders of the female genital tract that ...
Jingfang Li   +5 more
wiley   +1 more source

OsPT4 Facilitates Selenomethionine Transport and Biosynthesis to Enhance Seed Accumulation in Rice: Molecular Mechanisms and Biotechnological Potential

open access: yesPlant Biotechnology Journal, Volume 24, Issue 4, Page 1992-2008, April 2026.
ABSTRACT Selenium (Se) is a vital micronutrient for humans, with important functions for health and anti‐cancer properties. Organic Se shows higher antioxidant activity and much lower toxicity compared to inorganic Se, making it safer for use. Selenomethionine (SeMet) is one of the primary forms of organic Se.
Yang Yang   +11 more
wiley   +1 more source

Unexplained Infertility: An Update

open access: yesThe Obstetrician &Gynaecologist, Volume 28, Issue 2, Page 100-108, April 2026.
ABSTRACT Key Content Unexplained infertility accounts for up to 30% of cases of infertility. Potential causes for unexplained infertility have been proposed including reduced oocyte quality, poor endometrial receptivity, ovulatory PCOS, subclinical endometriosis and low semen quality.
Claudia Raperport   +3 more
wiley   +1 more source

Differential negative dominance by KCNA2 variants associated with global developmental delay suggests KCNA2 haploinsufficiency in humans

open access: yesThe Journal of Physiology, Volume 604, Issue 8, Page 3413-3430, 15 April 2026.
Abstract figure legend Potassium‐selective KV1.2 channels are encoded by the KCNA2 gene and regulate electrical signalling in neurons. KCNA2 genetic variants are associated with epileptic and developmental encephalopathy. We characterized two variants that subtly alter the channel's amino acid composition, p.H310D and p.G318D.
Pei Xin Boon   +8 more
wiley   +1 more source

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