Results 171 to 180 of about 13,008 (277)

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Damages of Freezing on the Development of Oocyte and Embryos [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: To assist save endangered species from extinction and to aid in their care, it is crucial to sustaining their reproductive capacity. The fetus's life and growth processes begin at conception and proceed in accordance with a biological clock'
Pegah Shayegh, Fatemeh Rahmati, Farzaneh Baniasadi, Meisam Jangkhah, Hasan Rajabimaham, Mohammad Reza Ghalamboran, Rouhollah Fathi   +6 more
doaj  

Epididymosome‐Supplemented Extender Induces Changes in Morpho‐Functional Traits and microRNA Levels of Post‐Thaw Sperm and Improves Embryo Developmental Potential

Molecular Reproduction and Development, Volume 93, Issue 8, August 2026.
ABSTRACT While molecular signature contributes to sperm quality and fertility potential, sperm may lost key molecules during cryopreservation. Since sperm cells are transcriptionally inert and rely on interactions with epididymosomes (epEVs) to acquire molecules, herein, we investigated the effects of the addition of epEVs to the cryopreservation ...
Laura Gabrielli Haupenthal, Maria Alice de Almeida, Cibele Maria Prado, Amanda Nespolo Silva, Gabriela Melendes Schneider, Paola Maria da Silva Rosa, Flávio Vieira Meirelles, Juliano Coelho da Silveira, Felipe Perecin, Maíra Bianchi Rodrigues Alves   +9 more
wiley   +1 more source

Improvement of cattle oocyte retrieval techniques and hormonal influence on in vitro embryonic development [PDF]

, 2015
Thesis (M. Sc. (Animal Production)) -- University of Limpopo, 2015The objectives of this study were: 1) To determine the effect of oocyte retrieval techniques (slicing and aspiration) on the quality and quantity of cattle oocytes, 2) To evaluate the ...
Lekola, Khomotso Podile Molvia
core  

Renal Phosphate Reabsorption in Humans Depends on at Least Three Distinct Transporters Unlike in Mice

Acta Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Aim Kidney excretion of phosphate is the gatekeeper of systemic phosphate homeostasis as evident from inborn and acquired diseases. Renal phosphate transporters are a promising target for phosphate‐lowering drugs, but molecular details of human kidney phosphate handling are largely unknown.
Ashley L. Fernandes, Laurine Lang, Jürgen Klar, Anja Giese, Alexander Ehrmann, Rupert Busch, Hannah Auwerx, Christoph Daniel, Nati Hernando, Isabel Rubio‐Aliaga, Carsten A. Wagner   +10 more
wiley   +1 more source

Spontaneous miscarriage after intracytoplasmic sperm injection with frozen sperm of patients with testicular germ cell tumour

BJU International, Volume 138, Issue 2, Page 315-323, August 2026.
Objective To clarify the impact of chromosomal aberrations on the offspring of patients with testicular germ cell tumour (TGCT) by evaluating the outcomes of intracytoplasmic sperm injection (ICSI). Patients and Methods Under the ethical review of Yokohama City University, 12 patients with TGCT and 25 with non‐TGCT cancer who had cryopreserved sperm ...
Haru Hamada, Akifumi Ijuin, Tomonari Hayama, Naoki Tsuchiya, Sumiko Sueyoshi, Misaki Toda, Ai Miyakoshi, Mayuko Kurumizaka, Marina Saito, Yuki Oike, Hiroe Ueno, Shinnosuke Kuroda, Kazumi Takeshima, Teppei Takeshima, Shin Saito, Ryoko Asano, Taichi Mizushima, Yasushi Yumura, Hideya Sakakibara, Etsuko Miyagi, Miki Tanoshima, Mariko Murase   +21 more
wiley   +1 more source

Implementation of immature oocytes by cryopreservation technique and subsquent in vitro maturation and fertilization post-thawing

, 2011
The aim of this study was to cryopreserve by vitrification by propylene glycol (PROH) and dimethylsulfoxide (DMSO) immature bovine oocytes in straws and to investigate the effects of vitrification on post-thaw oocyte maturation and fertilization. A total of 983 cumulus oocyte complexes were obtained by follicle aspiration from 263 ovaries of cows ...
openaire   +1 more source

Dynamics of human follicular growth and in-vitro oocyte maturation.

Human Reproduction Update, 1998
O. Salha, N. Abusheikha, V. Sharma
semanticscholar   +1 more source

Reply: Extracellular vesicle-mediated signalling in human rescue <i>in vitro</i> maturation: methodological and mechanistic considerations. [PDF]

Hum Reprod Open
Makieva S, Saenz-de-Juano MD, Almiñana C, Bauersachs S, Bernal-Ulloa S, Xie M, Velasco AG, Cervantes N, Sachs M, Ulbrich SE, Leeners B.   +10 more
europepmc   +1 more source

Heat Shock Affects Amino Acid Metabolism in Bovine Cumulus Cells and Denuded Oocytes During In Vitro Maturation. [PDF]

Biology (Basel)
Mzedawee HRH, Kowsar R, Manian G, Hajian M.   +3 more
europepmc   +1 more source