Results 71 to 80 of about 25,424 (210)

In vitro sperm generation from immature mouse testicular tissue using plasma rich in growth factors

open access: yesStem Cell Research & Therapy
Background Culture medium enriched with Knockout serum replacement (KSR) can produce in vitro mouse sperm, but it is inefficient, strain-specific and contains bovine products, which limits its use in the human clinic.
Seyyed Amir Moradian   +1 more
doaj   +1 more source

Insights into in vitro spermatogenesis in mammals: Past, present, future [PDF]

open access: yesMolecular Reproduction and Development, 2017
Considering the self‐renewal and differentiation ability of pluripotent stem cells, some studies have pointed out the possibility of stem cell‐derived sperm production. Most studies that test this hypothesis have been conducted on rodents, with some promising results; however, studies on humans are progressing slowly, and have encountered technical and
Amir Fattahi   +4 more
openaire   +2 more sources

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz   +3 more
wiley   +1 more source

Regulatory mechanisms of reproduction in locusts and grasshoppers

open access: yesNew Plant Protection, EarlyView.
Regulatory networks composed of numerous coding and noncoding genes play crucial roles in the reproduction of locusts and grasshoppers. This review integrates mechanistic advances in reproductive regulation, highlighting environmentally adaptive pathways and providing prospective targets for eco‐friendly pesticides.
Jing He, Jiliang Wang, Xinran Wang
wiley   +1 more source

Spermatogenesis in vitro: myth or reality?

open access: yes, 2022
In vitro spermatogenesis has been investigated using embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs) or spermatogonial stem cells (SSCs) by many laboratories worldwide. However, for human fertility preservation, patient-specific ESCs are not available and the safety of using these cells to generate gametes that transfer their genome
Lei, Qijing, Hamer, G.
openaire   +3 more sources

Establishment of a Southern catfish (Silurus meridionalis) spermatogonial stem cell line capable of sperm production in vitro

open access: yesAquaculture Reports
Southern catfish (Silurus meridionalis) is widely distributed in the Yangtze River and its tributaries and is valued for its rapid growth, nutritional content, pleasant taste, absence of intermuscular bone, and disease resistance.
Jianeng Li   +6 more
doaj   +1 more source

Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira   +8 more
wiley   +1 more source

Molecular characterization of transformer, transformer‐2, and doublesex genes in the carambola fruit fly, Bactrocera carambolae, revealing potential for genetic pest management

open access: yesInsect Science, EarlyView.
Abstract Globalization and climate change may be driving the spread of the quarantine fruit fly, Bactrocera carambolae, highlighting the need for ecofriendly control methods like the Sterile Insect Technique (SIT), which relies on releasing sterile males to reduce wild populations.
Kamoltip Laohakieat   +2 more
wiley   +1 more source

Recent Progress of Induced Spermatogenesis In Vitro

open access: yesInternational Journal of Molecular Sciences
Sperm, a crucial gamete for reproduction in sexual reproduction, is generated through the proliferation, differentiation, and morphological transformations of spermatogonial stem cells within the specialized microenvironment of the testes. Replicating this environment artificially presents challenges. However, interdisciplinary advancements in physics,
Siqi Liu   +6 more
openaire   +2 more sources

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