Results 81 to 90 of about 25,802 (201)

In vitro Spermatogenesis of Gypsy Moth Larvae

The American Biology Teacher, 1994
This laboratory activity is designed to offer students an opportunity to establish simple cell developmental cultures in order to observe the process of spermatogenesis, mitosis and meiosis in living cells. Insect cultures grow at room temperature and do not require a special incubator or complex growth media.
Judy Brown, Marcia J. Loeb
openaire   +1 more source

Ubiquitous Flame-Retardant Toxicants Impair Spermatogenesis in a Human Stem Cell Model

iScience, 2018
Summary: Sperm counts have rapidly declined in Western males over the past four decades. This rapid decline remains largely unexplained, but exposure to environmental toxicants provides one potential explanation for this decline.
Alyse N. Steves, Joshua M. Bradner, Kristen L. Fowler, Danielle Clarkson-Townsend, Brittany J. Gill, Adam C. Turry, W. Michael Caudle, Gary W. Miller, Anthony W.S. Chan, Charles A. Easley, IV   +9 more
doaj   +1 more source

Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism—A Systematic Review and Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben, Anne Prinsen, Laetitia de Kort, Jetske van Breda   +3 more
wiley   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Advances of three-dimensional (3D) culture systems for in vitro spermatogenesis. [PDF]

Stem Cell Res Ther, 2023
Salem M, Khadivi F, Javanbakht P, Mojaverrostami S, Abbasi M, Feizollahi N, Abbasi Y, Heidarian E, Rezaei Yazdi F.   +8 more
europepmc   +1 more source

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

Andrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus, André Acácio Souza da Silva, Olumide Stephen Akinsomisoye, Erick J. R. Silva, Paulo Sérgio Cerri, Salmo Azambuja de Oliveira, Estela Sasso‐Cerri   +6 more
wiley   +1 more source

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

Proteome of the testicular cell-conditioned medium supports germ cell differentiation in vitro

Journal of Advanced Veterinary and Animal Research
Objective: This study aimed to evaluate the effect of testicular cell conditioned medium (TCCM) on in vitro male germ cell differentiation and provide a proteomic profile of TCCM. Materials and Methods: TCCM was collected from 5-day-old mouse testicular
Wahono Esthi Prasetyaningtyas, Ni Wayan Kurniani Karja, Srihadi Agungpriyono, I Ketut Mudite Adnyane, Kusdiantoro Mohamad, Mokhamad Fahrudin   +5 more
doaj   +1 more source

In Vitro Sperm–Epididymosomes Interaction Immediately Before Fertilization Changes Sperm Fertility Potential

Andrology, EarlyView.
ABSTRACT Background Sperm acquire fertility ability during epididymal maturation mainly in the epididymal caput and corpus, and once matured, are stored in the epididymal cauda. During storage, interactions with cauda epididymosomes (epEVs) may influence sperm fertility potential; however, the role of such interactions on sperm fertility remains ...
Maíra Bianchi Rodrigues Alves, Maria Alice de Almeida, Ana Beatriz Bossois Moura, Laura Gabrielli Haupenthal, Raissa Braido Rangel, Flávio Vieira Meirelles, Juliano Coelho da Silveira, Felipe Perecin   +7 more
wiley   +1 more source

Cryopreservation and culture strategies for testicular tissue and cells in small and large animals

Frontiers in Veterinary Science
The preservation of testicular tissue and male germ cells represents a cutting-edge technique for safeguarding fertility, especially when sperm collection is not possible, such as in prepubertal animals, those that die unexpectedly or that receive ...
Valeria Vurchio, Martina Colombo, Rolando Pasquariello, Gaia Cecilia Luvoni   +3 more
doaj   +1 more source